begin name
tyson5
end name

begin reactions
v1 {1.0}$ext = {1.0}CycBT
v10 {1.0}$ext = {1.0}IEP
v11 {1.0}IEP = {1.0}$ext
v12 {1.0}$ext = {1.0}m
v13 {1.0}$ext = {1.0}SK
v14 {1.0}SK = {1.0}$ext
v2 {1.0}CycBT = {1.0}$ext
v3 {1.0}$ext = {1.0}Cdh1
v4 {1.0}Cdh1 = {1.0}$ext
v5 {1.0}$EXTERNAL = {1.0}Cdc20T
v6 {1.0}Cdc20T = {1.0}$ext
v7 {1.0}$ext = {1.0}Cdc20A
v8 {1.0}Cdc20A = {1.0}$ext
v9 {1.0}Cdc20A + {1.0}Cdc20T = {1.0}$ext
end reactions

begin rate equations
v1 = k1 + k0*SK[t]
v10 = CycB*k9*(1 - IEP[t])*m[t]
v11 = k10*IEP[t]
v12 = 0.005*(1 - m[t]/10)*m[t]
v13 = TF + k0*SK[t]
v14 = SK[t]
v2 = (k21 + Cdc20A[t] + k22*Cdh1[t])*CycBT[t]
v3 = ((k31 + k32*Cdc20A[t])*(1 - Cdh1[t]))/(1 + J3 - Cdh1[t])
v4 = (Cdh1[t]*(CycB*k4*m[t] + 2*SK[t]))/(J4 + Cdh1[t])
v5 = k51 + (k52*((CycB*m[t])/J5)^n)/(1 + ((CycB*m[t])/J5)^n)
v6 = k6*(-Cdc20A[t] + Cdc20T[t])
v7 = (k7*(-Cdc20A[t] + Cdc20T[t])*IEP[t])/(J7 - Cdc20A[t] + Cdc20T[t])
v8 = (k8*MAD*Cdc20A[t])/(J8 + Cdc20A[t])
v9 = k6*Cdc20A[t]
end rate equations

begin parameters
J3 = 0.04
J4 = 0.04
J5 = 0.3
J7 = 0.001
J8 = 0.001
MAD = 1.0
k0 = 0.0
k1 = 0.04
k10 = 0.02
k21 = 0.04
k22 = 1.0
k31 = 1.0
k32 = 10.0
k4 = 35.0
k51 = 0.005
k52 = 0.2
k6 = 0.1
k7 = 1.0
k8 = 0.5
k9 = 0.1
mu = 0.01
n = 4.0
ext = 0.0
defaultcompartment = 1.0
end parameters

begin initial conditions
Cdc20A[0] = Cdc20Ai
Cdc20T[0] = Cdc20Ti
Cdh1[0] = Cdh1i
CycBT[0] = CycBTi
IEP[0] = IEPi
SK[0] = SKi
m[0] = mi
end initial conditions

begin initial values
Cdc20Ai = 0.001
Cdc20Ti = 0.001
Cdh1i = 0.001
CycBTi = 0.001
IEPi = 0.001
SKi = 0.001
mi = 0.5
end initial values

begin assignment rules
CycB := CycBT[t]
TF := GK[1.5*m[t] + 0.05*SK[t], 1 + 3*CycB*m[t], 0.01, 0.01]
end assignment rules

begin function definitions
GK[a_,b_,c_,d_] := (2*a*d)/(-a + b + b*c + a*d + (-4*a*(-a + b)*d + (-a + b + b*c + a*d)^2)^0.5)
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units