begin name
silva
end name

begin reactions
v1 {1.0}$DHAP = {1.0}MG
v2 {1.0}$GAP = {1.0}MG
v3 {1.0}MG + {1.0}TSH2 = {1.0}HTA
v4 {1.0}HTA = {1.0}MG + {1.0}TSH2
v5 {1.0}HTA = {1.0}SDLTSH
v6 {1.0}SDLTSH = {1.0}TSH2
end reactions

begin rate equations
v1 = DHAP*k1
v2 = GAP*k2
v3 = k3*MG[t]*TSH2[t]
v4 = k4*HTA[t]
v5 = (V5*HTA[t])/(Km5 + HTA[t])
v6 = (V6*SDLTSH[t])/(Km6 + SDLTSH[t])
end rate equations

begin parameters
Km5 = 0.506
Km6 = 0.196
V5 = 6.084
V6 = 5.306
k1 = 0.0064
k2 = 0.00066
k3 = 0.34
k4 = 1.01
DHAP = 0.16
GAP = 0.0072
defaultcompartment = 1.0
end parameters

begin initial conditions
HTA[0] = HTAi
MG[0] = MGi
SDLTSH[0] = SDLTSHi
TSH2[0] = TSH2i
end initial conditions

begin initial values
HTAi = 0.14
MGi = 0.0
SDLTSHi = 0.0
TSH2i = 0.9
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units