begin name
rohwer2
end name

begin reactions
v1 {1.0}$PEP + {1.0}EI = {1.0}PyrPI
v10 {1.0}EIICBPGlc = {1.0}EIICB + {1.0}$GlcP
v2 {1.0}PyrPI = {1.0}$Pyr + {1.0}EIP
v3 {1.0}EIP + {1.0}HPr = {1.0}EIPHPr
v4 {1.0}EIPHPr = {1.0}EI + {1.0}HPrP
v5 {1.0}HPrP + {1.0}EIIA = {1.0}HPrPIIA
v6 {1.0}HPrPIIA = {1.0}HPr + {1.0}EIIAP
v7 {1.0}EIIAP + {1.0}EIICB = {1.0}EIIAPIICB
v8 {1.0}EIIAPIICB = {1.0}EIIA + {1.0}EIICBP
v9 {1.0}EIICBP + {1.0}$Glc = {1.0}EIICBPGlc
end reactions

begin rate equations
v1 = k1f*PEP*EI[t] - k1r*PyrPI[t]
v10 = -(GlcP*k10r*EIICB[t]) + k10f*EIICBPGlc[t]
v2 = -(k2r*Pyr*EIP[t]) + k2f*PyrPI[t]
v3 = -(k3r*EIPHPr[t]) + k3f*EIP[t]*HPr[t]
v4 = k4f*EIPHPr[t] - k4r*EI[t]*HPrP[t]
v5 = k5f*EIIA[t]*HPrP[t] - k5r*HPrPIIA[t]
v6 = -(k6r*EIIAP[t]*HPr[t]) + k6f*HPrPIIA[t]
v7 = -(k7r*EIIAPIICB[t]) + k7f*EIIAP[t]*EIICB[t]
v8 = k8f*EIIAPIICB[t] - k8r*EIIA[t]*EIICBP[t]
v9 = Glc*k9f*EIICBP[t] - k9r*EIICBPGlc[t]
end rate equations

begin parameters
k10f = 4800.0
k10r = 0.0054
k1f = 1960.0
k1r = 480000.0
k2f = 108000.0
k2r = 294.0
k3f = 14000.0
k3r = 14000.0
k4f = 84000.0
k4r = 3360.0
k5f = 21960.0
k5r = 21960.0
k6f = 4392.0
k6r = 3384.0
k7f = 880.0
k7r = 880.0
k8f = 2640.0
k8r = 960.0
k9f = 260.0
k9r = 389.0
Glc = 500.0
GlcP = 50.0
PEP = 2800.0
Pyr = 900.0
defaultcompartment = 1.0
end parameters

begin initial conditions
EI[0] = EIi
EIIA[0] = EIIAi
EIIAP[0] = EIIAPi
EIIAPIICB[0] = EIIAPIICBi
EIICB[0] = EIICBi
EIICBP[0] = EIICBPi
EIICBPGlc[0] = EIICBPGlci
EIP[0] = EIPi
EIPHPr[0] = EIPHPri
HPr[0] = HPri
HPrP[0] = HPrPi
HPrPIIA[0] = HPrPIIAi
PyrPI[0] = PyrPIi
end initial conditions

begin initial values
EIi = 3.0
EIIAi = 20.0
EIIAPi = 20.0
EIIAPIICBi = 0.0
EIICBi = 5.0
EIICBPi = 5.0
EIICBPGlci = 0.0
EIPi = 2.0
EIPHPri = 0.0
HPri = 25.0
HPrPi = 25.0
HPrPIIAi = 0.0
PyrPIi = 0.0
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units