#panteleev1



#reactions
reaction_1:
 {1.0}X + {1.0}VIIa_TF = {1.0}VIIa_TF_X
  compartment * (k1 * X * VIIa_TF - k2 * VIIa_TF_X)
reaction_2:
 {1.0}VIIa_TF_X = {1.0}VIIa_TF_Xa
  compartment * k1 * VIIa_TF_X
reaction_3:
 {1.0}VIIa_TF_Xa = {1.0}Xa + {1.0}VIIa_TF
  compartment * (k1 * VIIa_TF_Xa - k2 * Xa * VIIa_TF)
reaction_4:
 {1.0}Xa + {1.0}TFPI = {1.0}Xa_TFPI
  compartment * (k1 * Xa * TFPI - k2 * Xa_TFPI)
reaction_5:
 {1.0}VIIa_TF + {1.0}Xa_TFPI = {1.0}Xa_TFPI_VIIa_TF
  compartment * (k1 * VIIa_TF * Xa_TFPI - k2 * Xa_TFPI_VIIa_TF)
reaction_6:
 {1.0}VIIa_TF_Xa + {1.0}TFPI = {1.0}VIIa_TF_Xa_TFPI
  compartment * (k1 * VIIa_TF_Xa * TFPI - k2 * VIIa_TF_Xa_TFPI)
reaction_8:
 {1.0}VIIa_TF_X + {1.0}Xa_TFPI = {1.0}X + {1.0}VIIa_TF_Xa_TFPI
  compartment * (k1 * VIIa_TF_X * Xa_TFPI - k2 * X * VIIa_TF_Xa_TFPI)
reaction_9:
 {1.0}VIIa_TF_Xa_TFPI = {1.0}Xa_TFPI_VIIa_TF
  compartment * (k1 * VIIa_TF_Xa_TFPI - k2 * Xa_TFPI_VIIa_TF)


#parameters
reaction_1_k1 = 5.0
reaction_1_k2 = 770.0
reaction_2_k1 = 420.0
reaction_3_k1 = 770.0
reaction_3_k2 = 5.0
reaction_4_k1 = 0.054
reaction_4_k2 = 0.02
reaction_5_k1 = 0.44
reaction_5_k2 = 0.0
reaction_6_k1 = 6.0
reaction_6_k2 = 0.02
reaction_9_k1 = 0.0
reaction_9_k2 = 0.0
reaction_8_k1 = 20.0
reaction_8_k2 = 0.0
compartment = 1.0


#initial values
TFPI = 2.4
VIIa_TF = 1.0
VIIa_TF_X = 0.0
VIIa_TF_Xa = 0.0
VIIa_TF_Xa_TFPI = 0.0
X = 170.0
Xa = 0.0
Xa_TFPI = 0.0
Xa_TFPI_VIIa_TF = 0.0


#assignment rules