begin name
kouril8
end name

begin reactions
v1 {1.0}ATP + {1.0}P3G = {1.0}ADP + {1.0}BPG
v2 {1.0}ADP + {1.0}pep = {1.0}ATP + {1.0}pyr
v3 {1.0}BPG = {1.0}$pi + {1.0}P3G
v4 {1.0}nadph + {1.0}BPG = {1.0}$pi + {1.0}nadp + {1.0}gap
v5 {1.0}nadp + {1.0}glc = {1.0}nadph + {1.0}$GA
v6 {1.0}gap = {1.0}$sink
end reactions

begin rate equations
v1 = (protPGK*(-((VmrPGK*ADP[t]*BPG[t])/(KpgkADP*KpgkBPG)) + (VmfPGK*ATP[t]*P3G[t])/(KpgkATP*KpgkP3G)))/((1 + ADP[t]/KiADP)*(1 + ((1 + ADP[t]/KpgkADP)*BPG[t])/KpgkBPG + ((1 + ATP[t]/KpgkATP)*P3G[t])/KpgkP3G))
v2 = kPK*ADP[t]*pep[t]
v3 = kdbpg*BPG[t]
v4 = (protGAPdh*(-((pi*Vmarev*gap[t]*nadp[t])/(Kgap*Knadp*Kpi)) + (Vmfor*BPG[t]*nadph[t])/(KBPG*Knadph)))/((BPG[t]/KBPG + (1 + pi/Kpi)*(1 + gap[t]/Kgap))*(1 + nadp[t]/Knadp + nadph[t]/Knadph))
v5 = kGDH*glc[t]*nadp[t]
v6 = kdgap*gap[t]
end rate equations

begin parameters
KBPG = 0.0895997307185501
Kgap = 3.09006
KiADP = 1.01661161972841
Knadp = 0.204381
Knadph = 0.092444
KpgkADP = 0.374683891073216
KpgkATP = 9.30939957007288
KpgkBPG = 0.00824346710166223
KpgkP3G = 0.567800672197298
Kpi = 112.39
Vmarev = 35.871
VmfPGK = 17.2125572084323
Vmfor = 23.3991
VmrPGK = 37.9602642543915
kGDH = 10.0
kPK = 50.0
kdbpg = 0.736416
kdgap = 0.0559
protGAPdh = 0.0421
protPGK = 0.0045
sink2 = 0.0
GA = 0.0
pi = 0.0
sink = 0.0
default = 1.0
end parameters

begin initial conditions
ADP[0] = ADPi
ATP[0] = ATPi
BPG[0] = BPGi
P3G[0] = P3Gi
gap[0] = gapi
glc[0] = glci
nadp[0] = nadpi
nadph[0] = nadphi
pep[0] = pepi
pyr[0] = pyri
end initial conditions

begin initial values
ADPi = 0.0
ATPi = 10.0
BPGi = 0.0
P3Gi = 3.0
gapi = 0.0
glci = 10.0
nadpi = 0.0
nadphi = 0.2
pepi = 5.0
pyri = 0.4
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units