begin name
koster
end name

begin reactions
v1 {1.0}$XX = {1.0}RNA
v2 {1.0}RNA = {1.0}$XX
v3 {1.0}$XX = {1.0}Prot
v4 {1.0}Prot = {1.0}$XX
end reactions

begin rate equations
v1 = DNA*kRS*ng
v2 = kRd*RNA[t]
v3 = kPs*RNA[t]
v4 = kPd*Prot[t]
end rate equations

begin parameters
coef = 3.6
kPd = 0.0077
kPs = 343.0
kRd = 0.231
ktranscriptionattenuation = 14.0
mDNA = "3.15e-12"
mProt = 15300.0
nA = "6.02e+23"
nfac = 1.0
ng = 50.0
wfr = 0.236
XX = 0.0
defaultcompartment = 1.0
end parameters

begin initial conditions
Prot[0] = Proti
RNA[0] = RNAi
end initial conditions

begin initial values
Proti = 1330000000000.0
RNAi = 570000000.0
end initial values

begin assignment rules
kRS := Piecewise[{{540, t < 11.35}}, 540/ktranscriptionattenuation]
DNA := Piecewise[{{2, t < 0.917}, {4*2.71828^(1.188*(-1.5 + t)), t < 8.1 || nfac == 0}}, 1000*(10.1 + 12.1*(-8.1 + t) + 0.0000402*(-8.1 + t)^coef)]
LogDNA := Log[DNA]/Log[10]
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units