#koo1



#reactions
re10:
 {1.0}s11 = {1.0}s3
  dot_q_inpass
re11:
 {1.0}s13 = {1.0}s12
  unisec
re12:
 {1.0}s3 = {1.0}s9
  dot_Vp * pow(s3, 2) / (pow(K4, 2) + pow(s3, 2))
re3:
 {1.0}s4 = {1.0}s3
  -k6 * s3 * (B_T - s4) + k7 * s4
re4:
 {1.0}s5 = {1.0}s2
  k_CCE * (fracK * Cao / (K3 + Cao) - s2) * (s1 - s2)
re5:
 {1.0}s7 = {1.0}s6
  k1 * (R_T - half * R_T * (exp(-s12 / tau_I) + exp(-s12 / tau_II) + (exp(-s12 / tau_I) - exp(-s12 / tau_II)) * (tau_I + tau_II) / (tau_I - tau_II))) * s3 / (K1 + s3)
re6:
 {1.0}s6 = {1.0}s8
  k2 * s6
re7:
 {1.0}s2 = {1.0}s3
  k3 * (k_CICR * s3 / (K_CICR + s3)) * pow(s6 / (K2 + s6), 3) * s2 - k4 * pow(s3 / (K3 + s3), 2) + k5 * s2 * s2
re8:
 {1.0}s3 = {1.0}s9
  dot_Vhi * pow(s3, 4) / (pow(K_hi, 4) + pow(s3, 4))
re9:
 {1.0}s3 = {1.0}s10
  dot_Vex * s3 / (K5 + s3)


#parameters
B_T = 120000.0
Cao = 100.0
K1 = 0.0
K2 = 200.0
K3 = 150.0
K4 = 80.0
K5 = 321.0
K_CICR = 0.0
K_hi = 380.0
R_T = 44000.0
dot_Vex = 9165.0
dot_Vhi = 2380.0
dot_Vp = 815.0
dot_q_inpass = 3000.0
fracK = 7071067.81
half = 0.5
k1 = 0.0006
k2 = 1.0
k3 = 3.32
k4 = 2500.0
k5 = 5e-11
k6 = 0.05
k7 = 150.0
k_CCE = 0.0
k_CICR = 1.0
tau_I = 66.0
tau_II = 0.01
re11_unisec = 1.0
c1 = 1.0
c2 = 1.0
default = 1.0


#initial values
s1 = 1500000.0
s10 = 0.0
s11 = 0.0
s119 = 0.0
s12 = 0.0
s13 = 0.0
s2 = 2830000.0
s3 = 117.2
s4 = 3870.0
s5 = 0.0
s6 = 0.0
s7 = 0.0
s8 = 0.0
s9 = 0.0


#assignment rules