#kolodkin8



#reactions
v_1:
 {1.0}NRLnuc + {1.0}RE = {1.0}RENRLnuc
  (k5f*NRLnuc*RE - k5b*RENRLnuc)
v_2:
 {1.0}Impn + {1.0}NRLnuc = {1.0}ImpNRLn
  -(k4b*ImpNRLn) + k4f*Impn*NRLnuc
v_3:
 {1.0}Impc + {1.0}NRLcyt = {1.0}ImpNRLc
  -(k1b*ImpNRLc) + k1f*Impc*NRLcyt
v_4:
 {1.0}Impc = {3.44444444444444}Impn
  (Kap3f * Impc - Kap3b * Impn) / Vcytosol
v_5:
 {1.0}ImpNRLc = {3.44444444444444}ImpNRLn
  (Kap2f*ImpNRLc - Kap2b*ImpNRLn)/Vcytosol
v_6:
 {1.0}RENRLnuc = {1.0}Deg + {1.0}RE
  k6 * RENRLnuc + 0 * NRLnuc + 0 * RE + 0 * Impn + 0 * Impc + 0 * NRLcyt + 0 * ImpNRLc + 0 * RENRLnuc + 0 * ImpNRLn + 0 * Deg + 0 * NRLnuc + 0 * RE + 0 * Impn + 0 * Impc + 0 * NRLcyt + 0 * ImpNRLc + 0 * RENRLnuc + 0 * ImpNRLn + 0 * Deg


#parameters
EXTERNAL = 0.0
Kap2b = 5.4e-12
Kap2f = 5.4e-12
Kap3b = 5.4e-12
Kap3f = 5.4e-12
Vcytosol = 1.55e-12
Vnucleus = 4.5e-13
k1b = 300.0
k1f = 60.0
k4b = 300.0
k4f = 60.0
k5b = 60.0
k5f = 60.0
k6 = 0.1
default_compartment = 1.0


#initial values
Deg = 0.0
ImpNRLc = 0.0
ImpNRLn = 0.0
Impc = 0.84
Impn = 0.0
NRLcyt = 0.84
NRLnuc = 0.0
RE = 3.7
RENRLnuc = 0.0


#assignment rules