#kolodkin5

FIX: Lc

#reactions
v_1:
 {1.0}NRLn + {1.0}RE = {1.0}REL
  k1 * NRLn * RE - k2 * REL
v_2:
 {1.0}Lc = {1.0}Ln_
  TR(Kapf, Lc, Kapb, Ln_) / Vnucleus
v_3:
 {1.0}Ln_ + {1.0}NR = {1.0}NRLn
  k12 * Ln_ * NR - k22 * NRLn
v_4:
 {1.0}NRc = {1.0}NRLc
  k13 * Lc * NRc - k23 * NRLc
v_5:
 {1.0}NRc = {3.44444444444444}NR
  TR(Kapf4, NRc, Kapb4, NR)/Vcytosol
v_6:
 {1.0}NRLc = {3.44444444444444}NRLn
  TR(Kapf5, NRLc, Kapb5, NRLn) / Vcytosol + 0 * NRLn + 0 * RE + 0 * Ln_ + 0 * NR + 0 * NRc + 0 * NRLc + 0 * REL + 0 * NRLn + 0 * RE + 0 * Ln_ + 0 * NR + 0 * NRc + 0 * NRLc + 0 * REL


#parameters
EXTERNAL = 0.0
Kapb = 3.24e-11
Kapb4 = 5.4e-14
Kapb5 = 5.4e-14
Kapf = 3.24e-11
Kapf4 = 5.4e-12
Kapf5 = 5.4e-12
Vcytosol = 4.5e-13
Vnucleus = 1.55e-12
k1 = 60.0
k12 = 60.0
k13 = 60.0
k2 = 60.0
k22 = 60.0
k23 = 60.0
Lc = 0.005
default_compartment = 1.0


#initial values
Ln_ = 0.0
NR = 358.754
NRLc = 0.0
NRLn = 0.0
NRc = 3.58
RE = 3.7
REL = 0.0


#assignment rules