begin name
kim4
end name

begin reactions
React1 {1.0}$EXTERNAL = {1.0}R1
React10 {1.0}R2 = {1.0}$EXTERNAL
React11 {1.0}$EXTERNAL = {1.0}P2
React12 {1.0}P2 = {1.0}$EXTERNAL
React13 {1.0}$EXTERNAL = {1.0}P2prime
React14 {1.0}$EXTERNAL = {1.0}P2prime
React15 {1.0}P2prime = {1.0}$EXTERNAL
React16 {1.0}$EXTERNAL = {1.0}P3prime
React17 {1.0}P3prime = {1.0}$EXTERNAL
React18 {1.0}$EXTERNAL = {1.0}P2prime
React19 {1.0}$EXTERNAL = {1.0}P4prime
React2 {1.0}R1 = {1.0}$EXTERNAL
React20 {1.0}P4prime = {1.0}$EXTERNAL
React3 {1.0}$EXTERNAL = {1.0}P1
React4 {1.0}P1 = {1.0}$EXTERNAL
React5 {1.0}$EXTERNAL = {1.0}P1prime
React6 {1.0}$EXTERNAL = {1.0}P1prime
React7 {1.0}$EXTERNAL = {1.0}P1prime
React8 {1.0}P1prime = {1.0}$EXTERNAL
React9 {1.0}$EXTERNAL = {1.0}R2
end reactions

begin rate equations
React1 = i1
React10 = dR2*R2[t]
React11 = sP2R2*R2[t]
React12 = dP2*P2[t]
React13 = sP2primeP2*P2[t]
React14 = s2/(1 + P1prime[t]^n)
React15 = dP2prime*P2prime[t]
React16 = (sP3primeP2prime*P2prime[t]^n)/(1 + P2prime[t]^n)
React17 = dP3prime*P3prime[t]
React18 = s3/(1 + P4prime[t]^n)
React19 = (sP4primeP1prime*P1prime[t]^n)/(1 + P1prime[t]^n)
React2 = dR1*R1[t]
React20 = dP4prime*P4prime[t]
React3 = sP1R1*R1[t]
React4 = dP1*P1[t]
React5 = sP1primeP1*P1[t]
React6 = s1/(1 + P2prime[t]^n)
React7 = s3/(1 + P3prime[t]^n)
React8 = dP1prime*P1prime[t]
React9 = i2
end rate equations

begin parameters
dP1 = 0.22367
dP1prime = 0.37048
dP2 = 0.22367
dP2prime = 0.37048
dP3prime = 0.37048
dP4prime = 0.37048
dR1 = 0.23521
dR2 = 0.23521
n = 9.0
s1 = 0.4
s2 = 0.3
s3 = 0.2
sP1R1 = 0.47305
sP1primeP1 = 0.28687
sP2R2 = 0.47305
sP2primeP2 = 0.28687
sP3primeP2prime = 0.5
sP4primeP1prime = 0.5
compartment = 1.0
end parameters

begin initial conditions
P1[0] = P1i
P1prime[0] = P1primei
P2[0] = P2i
P2prime[0] = P2primei
P3prime[0] = P3primei
P4prime[0] = P4primei
R1[0] = R1i
R2[0] = R2i
end initial conditions

begin initial values
P1i = 0.1
P1primei = 0.1
P2i = 1.0
P2primei = 1.0
P3primei = 0.1
P4primei = 0.1
R1i = 0.01
R2i = 0.1
end initial values

begin assignment rules
i1 := Piecewise[{{1, t >= 50 && t <= 100}}, 0]
i2 := Piecewise[{{1, t >= 175 && t <= 225}}, 0]
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
React11 http://identifiers.org/go/GO:0006412
React3 http://identifiers.org/go/GO:0006412
end process annotations

begin species annotations
R1 http://identifiers.org/chebi/CHEBI:33699
R1 http://identifiers.org/kegg.compound/C00046
R2 http://identifiers.org/chebi/CHEBI:33699
R2 http://identifiers.org/kegg.compound/C00046
end species annotations

begin units
end units