#ihekwaba1

FIX: sink source

#reactions
v1:
 {1.0}NFkB + {1.0}IKKIkBa = {1.0}IKKIkBaNFkB
  k7 * IKKIkBa * NFkB
v10:
 {1.0}IkBb + {1.0}IKK = {1.0}IKKIkBb
  k40 * IKK * IkBb
v11:
 {1.0}IKKIkBb = {1.0}IKK
  k63 * IKKIkBb
v12:
 {1.0}IKKIkBb = {1.0}IKK + {1.0}IkBb
  k41 * IKKIkBb
v13:
 {1.0}NFkB + {1.0}IKKIkBe = {1.0}IKKIkBeNFkB
  k13 * IKKIkBe * NFkB
v14:
 {1.0}IKKIkBeNFkB = {1.0}NFkB + {1.0}IKK
  k15 * IKKIkBeNFkB
v15:
 {1.0}IKKIkBeNFkB = {1.0}NFkB + {1.0}IKKIkBe
  k14 * IKKIkBeNFkB
v16:
 {1.0}IkBe + {1.0}IKK = {1.0}IKKIkBe
  k46 * IKK * IkBe
v17:
 {1.0}IKKIkBe = {1.0}IKK
  k64 * IKKIkBe
v18:
 {1.0}IKKIkBe = {1.0}IkBe + {1.0}IKK
  k47 * IKKIkBe
v19:
 {1.0}IkBaNFkB + {1.0}IKK = {1.0}IKKIkBaNFkB
  k52 * IKK * IkBaNFkB
v2:
 {1.0}IKKIkBaNFkB = {1.0}NFkB + {1.0}IKK
  k9 * IKKIkBaNFkB
v20:
 {1.0}IKKIkBaNFkB = {1.0}IkBaNFkB + {1.0}IKK
  k53 * IKKIkBaNFkB
v21:
 {1.0}IkBbNFkB + {1.0}IKK = {1.0}IKKIkBbNFkB
  k55 * IKK * IkBbNFkB
v22:
 {1.0}IKKIkBbNFkB = {1.0}IkBbNFkB + {1.0}IKK
  k56 * IKKIkBbNFkB
v23:
 {1.0}IKK + {1.0}IkBeNFkB = {1.0}IKKIkBeNFkB
  k58 * IKK * IkBeNFkB
v24:
 {1.0}IKKIkBeNFkB = {1.0}IKK + {1.0}IkBeNFkB
  k59 * IKKIkBeNFkB
v25:
 {1.0}IkBa + {1.0}NFkB = {1.0}IkBaNFkB
  k1 * IkBa * NFkB
v26:
 {2.0}source = {1.0}IkBat + {2.0}sink
  k28 * NFkBn * NFkBn
v27:
 {1.0}IkBaNFkB = {1.0}IkBa + {1.0}NFkB
  k2 * IkBaNFkB
v28:
 {1.0}NFkBn + {1.0}IkBan = {1.0}IkBanNFkBn
  k21 * IkBan * NFkBn
v29:
 {1.0}IkBanNFkBn = {1.0}NFkBn + {1.0}IkBan
  k22 * IkBanNFkBn
v3:
 {1.0}IKKIkBaNFkB = {1.0}NFkB + {1.0}IKKIkBa
  k8 * IKKIkBaNFkB
v30:
 {1.0}IkBanNFkBn = {1.0}IkBaNFkB
  k54 * IkBanNFkBn
v31:
 {1.0}IkBaNFkB = {1.0}NFkB
  k16 * IkBaNFkB
v32:
 {1.0}IkBat = {1.0}sink
  k29 * IkBat
v33:
 {1.0}IkBan = {1.0}IkBa
  k39 * IkBan
v34:
 {1.0}IkBa = {1.0}IkBan
  k38 * IkBa
v35:
 {1.0}source = {1.0}IkBa + {1.0}sink
  k36 * IkBat
v36:
 {1.0}IkBb + {1.0}NFkB = {1.0}IkBbNFkB
  k3 * IkBb * NFkB
v37:
 {1.0}IkBbNFkB = {1.0}IkBb + {1.0}NFkB
  k4 * IkBbNFkB
v38:
 {1.0}IkBbn + {1.0}NFkBn = {1.0}IkBbnNFkBn
  k23 * IkBbn * NFkBn
v39:
 {1.0}IkBbnNFkBn = {1.0}IkBbn + {1.0}NFkBn
  k24 * IkBbnNFkBn
v4:
 {1.0}IKK + {1.0}IkBa = {1.0}IKKIkBa
  k34 * IKK * IkBa
v40:
 {1.0}IkBbnNFkBn = {1.0}IkBbNFkB
  k57 * IkBbnNFkBn
v41:
 {1.0}IkBbNFkB = {1.0}NFkB
  k17 * IkBbNFkB
v42:
 {1.0}IkBbt = {1.0}sink
  k31 * IkBbt
v43:
 {1.0}IkBbn = {1.0}IkBb
  k45 * IkBbn
v44:
 {1.0}IkBb = {1.0}IkBbn
  k44 * IkBb
v45:
 {1.0}source = {1.0}IkBb + {1.0}sink
  k42 * IkBbt
v46:
 {1.0}NFkB + {1.0}IkBe = {1.0}IkBeNFkB
  k5 * IkBe * NFkB
v47:
 {1.0}IkBeNFkB = {1.0}NFkB + {1.0}IkBe
  k6 * IkBeNFkB
v48:
 {1.0}NFkBn + {1.0}IkBen = {1.0}IkBenNFkBn
  k25 * IkBen * NFkBn
v49:
 {1.0}IkBenNFkBn = {1.0}IkBen + {1.0}NFkBn
  k26 * IkBenNFkBn
v5:
 {1.0}IKKIkBa = {1.0}IKK
  k62 * IKKIkBa
v50:
 {1.0}IkBenNFkBn = {1.0}IkBeNFkB
  k60 * IkBenNFkBn
v51:
 {1.0}IkBeNFkB = {1.0}NFkB
  k18 * IkBeNFkB
v52:
 {1.0}IkBet = {1.0}sink
  k33 * IkBet
v53:
 {1.0}IkBen = {1.0}IkBe
  k51 * IkBen
v54:
 {1.0}IkBe = {1.0}IkBen
  k50 * IkBe
v55:
 {1.0}source = {1.0}IkBe + {1.0}sink
  k48 * IkBet
v56:
 {1.0}NFkBn = {1.0}NFkB
  k20 * NFkBn
v57:
 {1.0}NFkB = {1.0}NFkBn
  k19 * NFkB
v58:
 {1.0}source = {1.0}IkBat
  k27 * source
v59:
 {1.0}source = {1.0}IkBbt
  k30 * source
v6:
 {1.0}IKKIkBa = {1.0}IKK + {1.0}IkBa
  k35 * IKKIkBa
v60:
 {1.0}source = {1.0}IkBet
  k32 * source
v61:
 {1.0}IkBa = {1.0}sink
  k37 * IkBa
v62:
 {1.0}IkBb = {1.0}sink
  k43 * IkBb
v63:
 {1.0}IkBe = {1.0}sink
  k49 * IkBe
v64:
 {1.0}IKK = {1.0}sink
  k61 * IKK
v7:
 {1.0}IKKIkBb + {1.0}NFkB = {1.0}IKKIkBbNFkB
  k10 * IKKIkBb * NFkB
v8:
 {1.0}IKKIkBbNFkB = {1.0}IKK + {1.0}NFkB
  k12 * IKKIkBbNFkB
v9:
 {1.0}IKKIkBbNFkB = {1.0}IKKIkBb + {1.0}NFkB
  k11 * IKKIkBbNFkB


#parameters
k1 = 0.5
k10 = 0.5
k11 = 0.0005
k12 = 0.0075
k13 = 0.5
k14 = 0.0005
k15 = 0.011
k16 = 2.25e-05
k17 = 2.25e-05
k18 = 2.25e-05
k19 = 0.09
k2 = 0.0005
k20 = 8e-05
k21 = 0.5
k22 = 0.0005
k23 = 0.5
k24 = 0.0005
k25 = 0.5
k26 = 0.0005
k27 = 1.54e-06
k28 = 0.0165
k29 = 0.00028
k3 = 0.5
k30 = 1.78e-07
k31 = 0.00028
k32 = 1.27e-07
k33 = 0.00028
k34 = 0.0225
k35 = 0.00125
k36 = 0.00408
k37 = 0.000113
k38 = 0.0003
k39 = 0.0002
k4 = 0.0005
k40 = 0.006
k41 = 0.00175
k42 = 0.00408
k43 = 0.000113
k44 = 0.00015
k45 = 0.0001
k46 = 0.009
k47 = 0.00175
k48 = 0.00408
k49 = 0.000113
k5 = 0.5
k50 = 0.00015
k51 = 0.0001
k52 = 0.185
k53 = 0.00125
k54 = 0.0138
k55 = 0.048
k56 = 0.00175
k57 = 0.0052
k58 = 0.07
k59 = 0.00175
k6 = 0.0005
k60 = 0.0052
k61 = 0.00012
k62 = 0.00407
k63 = 0.0015
k64 = 0.0022
k7 = 0.5
k8 = 0.0005
k9 = 0.0204
sink = 0.0
source = 1.0
compartment = 1.0


#initial values
IKK = 0.1
IKKIkBa = 0.0
IKKIkBaNFkB = 0.0
IKKIkBb = 0.0
IKKIkBbNFkB = 0.0
IKKIkBe = 0.0
IKKIkBeNFkB = 0.0
IkBa = 0.19028
IkBaNFkB = 0.082062
IkBan = 0.19326
IkBanNFkBn = 0.0013739
IkBat = 0.0054868
IkBb = 0.021428
IkBbNFkB = 0.0090963
IkBbn = 0.021887
IkBbnNFkBn = 0.00030061
IkBbt = 0.00063696
IkBe = 0.015307
IkBeNFkB = 0.0064977
IkBen = 0.015635
IkBenNFkBn = 0.00021473
IkBet = 0.000455
NFkB = 0.00025081
NFkBn = 0.00020366


#assignment rules