#goldbeter5

FIX: EmptySet

#reactions
rM:
 {1.0}EmptySet = {1.0}M
  default * Vs * pow(KI, n) / (pow(KI, n) + pow(Pn, n))
rP01:
 {1.0}P0 = {1.0}P1
  CYTOPLASM * V1 * P0 / (K1 + P0)
rP10:
 {1.0}P1 = {1.0}P0
  CYTOPLASM * V2 * P1 / (K2 + P1)
rP12:
 {1.0}P1 = {1.0}P2
  CYTOPLASM * V3 * P1 / (K3 + P1)
rP21:
 {1.0}P2 = {1.0}P1
  CYTOPLASM * V4 * P2 / (K4 + P2)
rP2n:
 {1.0}P2 = {1.0}Pn
  k1 * P2 * CYTOPLASM
rPn2:
 {1.0}Pn = {1.0}P2
  k2 * Pn * compartment_0000004
rTL:
 {1.0}EmptySet = {1.0}P0
  ks * M * default
rVd:
 {1.0}P2 = {1.0}EmptySet
  CYTOPLASM * Vd * P2 / (Kd + P2)
rmRNAd:
 {1.0}M = {1.0}EmptySet
  Vm * M * CYTOPLASM / (Km + M)


#parameters
EmptySet = 0.0
rM_Vs = 0.76
rM_KI = 1.0
rM_n = 4.0
rTL_ks = 0.38
rP01_V1 = 3.2
rP01_K1 = 2.0
rP10_V2 = 1.58
rP10_K2 = 2.0
rP12_V3 = 5.0
rP12_K3 = 2.0
rP21_V4 = 2.5
rP21_K4 = 2.0
rP2n_k1 = 1.9
rPn2_k2 = 1.3
rmRNAd_Km = 0.5
rmRNAd_Vm = 0.65
rVd_Vd = 0.95
rVd_Kd = 0.2
CYTOPLASM = 1e-15
compartment_0000004 = 1e-15
default = 1e-15


#initial values
M = 0.1
P0 = 0.25
P1 = 0.25
P2 = 0.25
Pn = 0.25


#assignment rules
!F Pt = P0 + P1 + P2 + Pn