begin name
goldbeter5
end name

begin reactions
rM {1.0}$EmptySet = {1.0}M
rP01 {1.0}P0 = {1.0}P1
rP10 {1.0}P1 = {1.0}P0
rP12 {1.0}P1 = {1.0}P2
rP21 {1.0}P2 = {1.0}P1
rP2n {1.0}P2 = {1.0}Pn
rPn2 {1.0}Pn = {1.0}P2
rTL {1.0}$EmptySet = {1.0}P0
rVd {1.0}P2 = {1.0}$EmptySet
rmRNAd {1.0}M = {1.0}$EmptySet
end reactions

begin rate equations
rM = (default*rMKI^rMn*rMVs)/(rMKI^rMn + Pn[t]^rMn)
rP01 = (CYTOPLASM*rP01V1*P0[t])/(rP01K1 + P0[t])
rP10 = (CYTOPLASM*rP10V2*P1[t])/(rP10K2 + P1[t])
rP12 = (CYTOPLASM*rP12V3*P1[t])/(rP12K3 + P1[t])
rP21 = (CYTOPLASM*rP21V4*P2[t])/(rP21K4 + P2[t])
rP2n = CYTOPLASM*rP2nk1*P2[t]
rPn2 = compartment0000004*rPn2k2*Pn[t]
rTL = default*rTLks*M[t]
rVd = (CYTOPLASM*rVdVd*P2[t])/(rVdKd + P2[t])
rmRNAd = (CYTOPLASM*rmRNAdVm*M[t])/(rmRNAdKm + M[t])
end rate equations

begin parameters
EmptySet = 0.0
rMVs = 0.76
rMKI = 1.0
rMn = 4.0
rTLks = 0.38
rP01V1 = 3.2
rP01K1 = 2.0
rP10V2 = 1.58
rP10K2 = 2.0
rP12V3 = 5.0
rP12K3 = 2.0
rP21V4 = 2.5
rP21K4 = 2.0
rP2nk1 = 1.9
rPn2k2 = 1.3
rmRNAdKm = 0.5
rmRNAdVm = 0.65
rVdVd = 0.95
rVdKd = 0.2
CYTOPLASM = "1e-15"
compartment0000004 = "1e-15"
default = "1e-15"
end parameters

begin initial conditions
M[0] = Mi
P0[0] = P0i
P1[0] = P1i
P2[0] = P2i
Pn[0] = Pni
end initial conditions

begin initial values
Mi = 0.1
P0i = 0.25
P1i = 0.25
P2i = 0.25
Pni = 0.25
end initial values

begin assignment rules
Pt := P0[t] + P1[t] + P2[t] + Pn[t]
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
Pn http://identifiers.org/uniprot/P07663
Pt http://identifiers.org/uniprot/P07663
end species annotations

begin units
end units