#francois1



#reactions
A_binds_gB:
 {1.0}A + {1.0}gB = {1.0}AgB
  cell * alpha * A * gB
basal_transcription_B:
 $pool = {1.0}rB
  cell * transcription_and_translation(rhof, gB)
degradation_A:
 {1.0}A = $pool
  cell * deltaA * A
degradation_B:
 {1.0}B = $pool
  cell * deltaB * B
degradation_dimer:
 {1.0}AB = $pool
  cell * deltaAB * AB
degradation_mRNA_B:
 {1.0}rB = $pool
  cell * deltar * rB
formation_dimer:
 {1.0}A + {1.0}B = {1.0}AB
  cell * gamma * A * B
gB_releases_A:
 {1.0}AgB = {1.0}A + {1.0}gB
  cell * theta * AgB
production_A:
 $pool = {1.0}A
  cell * Constant_flux__irreversible(rhoA)
stim_transcription_B:
 $pool = {1.0}rB
  cell * transcription_and_translation(rhob, AgB)
translation_B:
 $pool = {1.0}B
  cell * transcription_and_translation(beta, rB)


#parameters
alpha = 0.001
beta = 3.0
deltaA = 0.01
deltaAB = 0.01
deltaB = 0.01
deltar = 0.03
gamma = 1.0
rhoA = 100.0
rhob = 5.0
rhof = 0.1
theta = 0.04
cell = 1.0


#initial values
A = 40.0
AB = 0.0
AgB = 0.0
B = 0.0
gB = 1.0
rB = 0.0


#assignment rules