begin name
edelstein1
end name

begin reactions
v1 {1.0}Basal = {1.0}BasalACh
v10 {1.0}ActiveVar = {1.0}Intermediate
v11 {1.0}ActiveACh = {1.0}IntermediateACh
v12 {1.0}ActiveACh2 = {1.0}IntermediateACh2
v13 {1.0}Desensitised = {1.0}DesensitisedACh
v14 {1.0}DesensitisedACh = {1.0}DesensitisedACh2
v15 {1.0}Intermediate = {1.0}Desensitised
v16 {1.0}IntermediateACh = {1.0}DesensitisedACh
v17 {1.0}IntermediateACh2 = {1.0}DesensitisedACh2
v2 {1.0}BasalACh = {1.0}BasalACh2
v3 {1.0}BasalACh2 = {1.0}ActiveACh2
v4 {1.0}ActiveVar = {1.0}ActiveACh
v5 {1.0}ActiveACh = {1.0}ActiveACh2
v6 {1.0}Basal = {1.0}ActiveVar
v7 {1.0}BasalACh = {1.0}ActiveACh
v8 {1.0}Intermediate = {1.0}IntermediateACh
v9 {1.0}IntermediateACh = {1.0}IntermediateACh2
end reactions

begin rate equations
v1 = kf0*Basal[t] - kr0*BasalACh[t]
v10 = kf9*ActiveVar[t] - kr9*Intermediate[t]
v11 = kf10*ActiveACh[t] - kr10*IntermediateACh[t]
v12 = kf11*ActiveACh2[t] - kr11*IntermediateACh2[t]
v13 = kf12*Desensitised[t] - kr12*DesensitisedACh[t]
v14 = kf13*DesensitisedACh[t] - kr13*DesensitisedACh2[t]
v15 = -(kr14*Desensitised[t]) + kf14*Intermediate[t]
v16 = -(kr15*DesensitisedACh[t]) + kf15*IntermediateACh[t]
v17 = -(kr16*DesensitisedACh2[t]) + kf16*IntermediateACh2[t]
v2 = kf1*BasalACh[t] - kr1*BasalACh2[t]
v3 = -(kr2*ActiveACh2[t]) + kf2*BasalACh2[t]
v4 = -(kr3*ActiveACh[t]) + kf3*ActiveVar[t]
v5 = kf4*ActiveACh[t] - kr4*ActiveACh2[t]
v6 = -(kr5*ActiveVar[t]) + kf5*Basal[t]
v7 = -(kr6*ActiveACh[t]) + kf6*BasalACh[t]
v8 = kf7*Intermediate[t] - kr7*IntermediateACh[t]
v9 = kf8*IntermediateACh[t] - kr8*IntermediateACh2[t]
end rate equations

begin parameters
EXTERNAL = 0.0
comp1 = "1e-16"
kf0 = 3000.0
kf1 = 1500.0
kf10 = 19.85
kf11 = 20.0
kf12 = 3000.0
kf13 = 1500.0
kf14 = 0.05
kf15 = 0.05
kf16 = 0.05
kf2 = 30000.0
kf3 = 3000.0
kf4 = 1500.0
kf5 = 0.54
kf6 = 130.0
kf7 = 3000.0
kf8 = 1500.0
kf9 = 19.7
kr0 = 8000.0
kr1 = 16000.0
kr10 = 1.74
kr11 = 0.81
kr12 = 4.0
kr13 = 8.0
kr14 = 0.0012
kr15 = 0.0012
kr16 = 0.0012
kr2 = 700.0
kr3 = 8.64
kr4 = 17.28
kr5 = 10800.0
kr6 = 2740.0
kr7 = 4.0
kr8 = 8.0
kr9 = 3.74
t2 = 20.0
defaultcompartment = 1.0
end parameters

begin initial conditions
ActiveACh[0] = ActiveAChi
ActiveACh2[0] = ActiveACh2i
ActiveVar[0] = ActiveVari
Basal[0] = Basali
BasalACh[0] = BasalAChi
BasalACh2[0] = BasalACh2i
Desensitised[0] = Desensitisedi
DesensitisedACh[0] = DesensitisedAChi
DesensitisedACh2[0] = DesensitisedACh2i
Intermediate[0] = Intermediatei
IntermediateACh[0] = IntermediateAChi
IntermediateACh2[0] = IntermediateACh2i
end initial conditions

begin initial values
ActiveAChi = 0.0
ActiveACh2i = 0.0
ActiveVari = 0.0
Basali = 1.53757e-05
BasalAChi = 0.0
BasalACh2i = 0.0
Desensitisedi = 0.0
DesensitisedAChi = 0.0
DesensitisedACh2i = 0.0
Intermediatei = 0.0
IntermediateAChi = 0.0
IntermediateACh2i = 0.0
end initial values

begin assignment rules
end assignment rules

begin function definitions
end function definitions

begin events
end events

begin process annotations
end process annotations

begin species annotations
end species annotations

begin units
end units