(* Generated by JWS Online *) (* This is an experimental feature of JWS Online. Please report any mistakes.*) (* Note that the following notable SBML entities or features are not supported in notebook outputyet: *) (* Events *) (* Constraints *) (* Units and UnitDefinitions *) (* AlgebraicRules *) (* conversionFactors *) variables = { x[t], y[t], z[t] }; initialValues = { x[0] == 2.5, y[0] == 0.07, z[0] == 0.5 }; rates = { v1, v2, v3, v4, v5, v6, v7 }; rateEquations = { v1 -> lambda, v2 -> d*x[t], v3 -> beta*s*x[t]*y[t], v4 -> a*y[t], v5 -> p*y[t]*z[t], v6 -> c*y[t], v7 -> b*z[t] }; parameters = { a -> 0.02, b -> 0.15, beta -> 0.5, c -> 1.0, d -> 0.02, lambda -> 0.05, p -> 1.0, s -> 0.0, default -> 1.0 }; assignments = { v -> 1000000*y[t] }; events = { }; speciesAnnotations = { }; reactionAnnotations = { }; units = { {"time" -> "", "metabolite" -> "", "extent" -> ""} }; (* Time evolution *) odes = { x'[t] == 1.0*v1 -1.0*v2 -1.0*v3, y'[t] == 1.0*v3 -1.0*v5 -1.0*v4, z'[t] == 1.0*v6 -1.0*v7 }; timeCourse = NDSolve[Join[odes, initialValues]//.rateEquations//.assignments//.parameters, variables, {t, 0, 100}]; (* Steady-state solution initialized with result of time evolution *) findRootEquations = odes /.D[_[t],t]->0; findRootVariables = Partition[Flatten[{#, #/.timeCourse/.t->100} &/@variables],2]; steadyStateVariables = FindRoot[findRootEquations//.rateEquations//.assignments//.parameters, findRootVariables, MaxIterations->100] fluxes = #//.assignments//.parameters/.steadyStateVariables&/@rateEquations (* Plot the time evolution of the variables *) plotTable=Table[Plot[variables[[i]]/.parameters/.timeCourse,{t,0,100},PlotLegends->variables[[i]],PlotRange->Full],{i,Length[variables]}]