#albert1 FIX: species_25 species_26 species_27 #reactions vAKc: {1.0}species_3 + {1.0}species_6 = {2.0}species_2 compartment_1 * function_22(k, species_3, species_6, keqak, species_2) vAKg: {1.0}species_11 + {1.0}species_13 = {2.0}species_12 compartment_2 * function_22(k, species_11, species_13, keqak, species_12) vALD: {1.0}species_16 = {1.0}species_17 + {1.0}species_18 compartment_2 * function_14(Vmax_v5, species_16, species_18, species_17, Keq_v5, species_11, species_12, species_13, r_v5, KGAP_v5, KGAPi_v5) vANTI: {1.0}species_22 + {1.0}species_8 = {1.0}species_9 + {1.0}species_17 k1 * species_22 * species_8 - k2 * species_9 * species_17 vAU: {1.0}species_3 = {1.0}species_2 compartment_1 * function_20(k, species_3, species_2) vENO: {1.0}species_5 = {1.0}species_4 RaENO * compartment_1 * function_12(species_5, species_4, Kms, Kmp, Vf, Vr) vGAPDH: {1.0}species_18 + {1.0}species_19 = {1.0}species_21 + {1.0}species_20 compartment_2 * function_15(Vmax_v7, species_18, KGAP_v7, species_19, KNAD_v7, r_v7, species_21, KBPGA13_v7, species_20, KNADH_v7) vGK: {1.0}species_22 + {1.0}species_12 = {1.0}species_24 + {1.0}species_11 compartment_2 * function_21(Vmax_v14, species_22, KGly3Pg_v14, species_12, KADPg_v14, r_v14, species_24, KGlycerol_v14, species_11, KATPg_v14) vGPDH: {1.0}species_17 + {1.0}species_20 = {1.0}species_19 + {1.0}species_22 compartment_2 * function_16(Vmax_v8, species_17, KDHAPg_v8, species_20, KNADH_v8, r_v8, species_19, KNAD_v8, species_22, KGly3Pg_v8) vGPO: {1.0}species_9 = {1.0}species_8 compartment_1 * function_17(species_9, Km, V) vGT: {1.0}species_25 = {1.0}species_10 function_10(Vmax_v1, species_25, species_10, KGlc, Alpha_v1) vGlyT: {1.0}species_24 = {1.0}species_27 k1 * species_24 - k2 * species_27 vHK: {1.0}species_10 + {1.0}species_11 = {1.0}species_14 + {1.0}species_12 RaHXK * compartment_2 * function_11(Vmax_v2, species_10, KGlcInt_v2, species_11, KATPg_v2, species_12, KADPg_v2, species_14, KGlc6P_v2) vPFK: {1.0}species_15 + {1.0}species_11 = {1.0}species_16 + {1.0}species_12 RaPFK * compartment_2 * function_13(Vmax_v4, Ki1Fru16BP_v4, species_16, species_15, KFru6P_v4, species_11, KATPg_v4, Ki2Fru16BP_v4) vPGI: {1.0}species_14 = {1.0}species_15 compartment_2 * function_12(species_14, species_15, Kms, Kmp, Vf, Vr) vPGK: {1.0}species_21 + {1.0}species_12 = {1.0}species_23 + {1.0}species_11 compartment_2 * function_18(Vmax_v11, species_21, KBPGA13_v11, species_12, KADPg_v11, r_v11, species_23, KPGA3_v11, species_11, KATPg_v11) vPGM: {1.0}species_7 = {1.0}species_5 RaPGAM * compartment_1 * function_12(species_7, species_5, Kms, Kmp, Vf, Vr) vPGT: {1.0}species_23 = {1.0}species_7 k1 * species_23 - k2 * species_7 vPK: {1.0}species_4 + {1.0}species_2 = {1.0}species_1 + {1.0}species_3 RaPYK * compartment_1 * function_19(Vmax_v12, species_4, PK_n, species_2, KADP_v12, species_3) vPT: {1.0}species_1 = {1.0}species_26 function_17(species_1, Km, V) vTPI: {1.0}species_17 = {1.0}species_18 compartment_2 * function_12(species_17, species_18, Kms, Kmp, Vf, Vr) #parameters RaENO = 1.0 RaHXK = 1.0 RaPFK = 1.0 RaPGAM = 1.0 RaPYK = 1.0 species_25 = 5.0 species_26 = 0.0 species_27 = 0.0 vHK_KATPg_v2 = 0.116 vGT_Vmax_v1 = 108.9 vGT_KGlc = 1.0 vGT_Alpha_v1 = 0.75 vHK_Vmax_v2 = 1929.0 vHK_KGlcInt_v2 = 0.1 vHK_KADPg_v2 = 0.126 vHK_KGlc6P_v2 = 12.0 vPGI_Kms = 0.4 vPGI_Kmp = 0.12 vPGI_Vf = 1305.0 vPGI_Vr = 1305.0 vPFK_Vmax_v4 = 1708.0 vPFK_Ki1Fru16BP_v4 = 15.8 vPFK_KFru6P_v4 = 0.82 vPFK_KATPg_v4 = 0.026 vPFK_Ki2Fru16BP_v4 = 10.7 vALD_Vmax_v5 = 560.0 vALD_Keq_v5 = 0.069 vALD_r_v5 = 1.19 vALD_KGAP_v5 = 0.067 vALD_KGAPi_v5 = 0.098 vTPI_Kms = 1.2 vTPI_Kmp = 0.25 vTPI_Vf = 999.3 vTPI_Vr = 5696.01 vGAPDH_Vmax_v7 = 720.9 vGAPDH_KGAP_v7 = 0.15 vGAPDH_KNAD_v7 = 0.45 vGAPDH_r_v7 = 0.67 vGAPDH_KBPGA13_v7 = 0.1 vGAPDH_KNADH_v7 = 0.02 vGPDH_Vmax_v8 = 465.0 vGPDH_KDHAPg_v8 = 0.1 vGPDH_KNADH_v8 = 0.01 vGPDH_r_v8 = 0.28 vGPDH_KNAD_v8 = 0.4 vGPDH_KGly3Pg_v8 = 2.0 vGPO_Km = 1.7 vGPO_V = 368.0 vPT_Km = 1.96 vPT_V = 200.0 vPGK_Vmax_v11 = 2862.0 vPGK_KBPGA13_v11 = 0.003 vPGK_KADPg_v11 = 0.1 vPGK_r_v11 = 0.47 vPGK_KPGA3_v11 = 1.62 vPGK_KATPg_v11 = 0.29 vPK_Vmax_v12 = 1020.0 vPK_PK_n = 2.5 vPK_KADP_v12 = 0.114 vAU_k = 50.0 vGK_Vmax_v14 = 200.0 vGK_KGly3Pg_v14 = 3.83 vGK_KADPg_v14 = 0.56 vGK_r_v14 = 60.86 vGK_KGlycerol_v14 = 0.44 vGK_KATPg_v14 = 0.24 vPGM_Kms = 0.27 vPGM_Kmp = 0.11 vPGM_Vf = 225.0 vPGM_Vr = 495.0 vENO_Kms = 0.054 vENO_Kmp = 0.24 vENO_Vf = 598.0 vENO_Vr = 394.68 vAKc_k = 1000000.0 vAKc_keqak = 0.442 vAKg_k = 1000000.0 vAKg_keqak = 0.442 vPGT_k1 = 1000000.0 vPGT_k2 = 1000000.0 vANTI_k1 = 1000000.0 vANTI_k2 = 1000000.0 vGlyT_k1 = 1000000.0 vGlyT_k2 = 1000000.0 compartment_1 = 1.0 compartment_2 = 1.0 compartment_3 = 1.0 #initial values species_1 = 10.0 species_10 = 0.0 species_11 = 0.240501857508 species_12 = 1.51899628498 species_13 = 4.24050185751 species_14 = 0.5 species_15 = 0.5 species_16 = 10.0 species_17 = 8.47911460193 species_18 = 2.5 species_19 = 2.0 species_2 = 1.31652277625 species_20 = 2.0 species_21 = 0.5 species_22 = 10.5208853981 species_23 = 0.0 species_24 = 0.0 species_3 = 0.341738611875 species_4 = 0.0 species_5 = 0.0 species_6 = 2.24173861188 species_7 = 0.0 species_8 = 2.23134594788 species_9 = 2.76865405212 #assignment rules