#achcar3

FIX: Glce Glye Pig Pyre

#reactions
AKc:
 {2.0}ADPc = {1.0}AMPc + {1.0}ATPc
  (AKcAKck1*ADPc**2-AKcAKck2*AMPc*ATPc)/cytosol
AKg:
 {44.5116}ADPg = {22.2558}AMPg + {22.2558}ATPg
  (AKgAKgk1*ADPg**2-AKgAKgk2*AMPg*ATPg)/cytosol
ALDg:
 {22.2558}Fru16BPg = {22.2558}DHAPg + {22.2558}GA3Pg
  (ALDgALDgVmax*Fru16BPg*(1.-(DHAPg*GA3Pg)/(ALDgALDgKeq*Fru16BPg)))/(ALDgALDgKmFru16BP*cytosol*(1.+ADPg/ALDgALDgKiADP+AMPg/ALDgALDgKiAMP+ATPg/ALDgALDgKiATP)*(1.+DHAPg/ALDgALDgKmDHAP+Fru16BPg/(ALDgALDgKmFru16BP*(1.+ADPg/ALDgALDgKiADP+AMPg/ALDgALDgKiAMP+ATPg/ALDgALDgKiATP))+GA3Pg/ALDgALDgKmGA3P+(DHAPg*GA3Pg)/(ALDgALDgKmDHAP*ALDgALDgKmGA3P)+(Fru16BPg*GA3Pg)/(ALDgALDgKiGA3P*ALDgALDgKmFru16BP*(1.+ADPg/ALDgALDgKiADP+AMPg/ALDgALDgKiAMP+ATPg/ALDgALDgKiATP))))
ATPuc:
 {1.0}ATPc = {1.0}ADPc
  (ATPucATPuck*ATPc)/(cytosol*ADPc)
DHAPtg:
 {1.0}DHAPc = {22.2558}DHAPg
  (DHAPtgDHAPtgk*(DHAPc-DHAPg))/cytosol
ENOc:
 {1.0}PGA2c = {1.0}PEPc
  (ENOcENOcVmax*(1-PEPc/(ENOcENOcKeq*PGA2c))*PGA2c)/(cytosol*ENOcENOcKmPGA2*(1.+PEPc/ENOcENOcKmPEP+PGA2c/ENOcENOcKmPGA2))
G3PDHg:
 {22.2558}DHAPg + {22.2558}NADHg = {22.2558}Gly3Pg + {22.2558}NADg
  (G3PDHgG3PDHgVmax*DHAPg*NADHg*(1.-(Gly3Pg*NADg)/(G3PDHgG3PDHgKeq*DHAPg*NADHg)))/(cytosol*G3PDHgG3PDHgKmDHAP*G3PDHgG3PDHgKmNADH*(1.+DHAPg/G3PDHgG3PDHgKmDHAP+Gly3Pg/G3PDHgG3PDHgKmGly3P)*(1.+NADHg/G3PDHgG3PDHgKmNADH+NADg/G3PDHgG3PDHgKmNAD))
GA3Ptg:
 {22.2558}GA3Pg = {1.0}GA3Pc
  (GA3PtgGA3Ptgk*(-GA3Pc+GA3Pg))/cytosol
GAPDHg:
 {1.0}Pig + {22.2558}GA3Pg + {22.2558}NADg = {22.2558}BPGA13g + {22.2558}NADHg
  (GAPDHgGAPDHgVmax*GA3Pg*NADg*(1.-(NADHg*BPGA13g)/(GAPDHgGAPDHgKeq*GA3Pg*NADg)))/(cytosol*GAPDHgGAPDHgKmGA3P*GAPDHgGAPDHgKmNAD*(1.+NADHg/GAPDHgGAPDHgKmNADH+NADg/GAPDHgGAPDHgKmNAD)*(1.+GA3Pg/GAPDHgGAPDHgKmGA3P+BPGA13g/GAPDHgGAPDHgKmBPGA13))
GKg:
 {22.2558}ADPg + {22.2558}Gly3Pg = {22.2558}ATPg + {22.2558}Glyg
  (GKgGKgVmax*ADPg*Gly3Pg*(1.-(ATPg*Glyg)/(GKgGKgKeq*ADPg*Gly3Pg)))/(cytosol*GKgGKgKmADP*GKgGKgKmGly3P*(1.+ADPg/GKgGKgKmADP+ATPg/GKgGKgKmATP)*(1.+Gly3Pg/GKgGKgKmGly3P+Glyg/GKgGKgKmGly))
GPOc:
 {1.0}Gly3Pc = {1.0}DHAPc
  (GPOcGPOcVmax*Gly3Pc)/(cytosol*GPOcGPOcKmGly3P*(1.+((1.+SHAM/GPOcGPOcKiSHAM)*Gly3Pc)/GPOcGPOcKmGly3P))
GlcTc:
 {1.0}Glce = {1.0}Glcc
  (GlcTcGlcTcVmax*(Glce-Glcc))/(cytosol*(GlcTcGlcTcKmGlc+Glce+Glcc+(GlcTcGlcTcalpha*Glce*Glcc)/GlcTcGlcTcKmGlc))
GlcTg:
 {1.0}Glcc = {22.2558}Glcg
  (GlcTgGlcTgk*Glcc-GlcTgGlcTgk*Glcg)/cytosol
Gly3Ptg:
 {22.2558}Gly3Pg = {1.0}Gly3Pc
  (Gly3PtgGly3Ptgk*(-Gly3Pc+Gly3Pg))/cytosol
GlyTc:
 {1.0}Glyc = {1.0}Glye
  (GlyTcGlyTck*(-Glye+Glyc)+(GlyTcGlyTcVrmax*GlyTcGlyTcy*(-Glye+Glyc))/(GlyTcGlyTcKmGlye*GlyTcGlyTcy+GlyTcGlyTcy*Glye+Glyc+(GlyTcGlyTcx*(1.-GlyTcGlyTcx+GlyTcGlyTcy)*Glye*Glyc)/(GlyTcGlyTcKmGlye*GlyTcGlyTcy)))/cytosol
Glytg:
 {22.2558}Glyg = {1.0}Glyc
  (GlytgGlytgk*(-Glyc+Glyg))/cytosol
HXKg:
 {22.2558}ATPg + {22.2558}Glcg = {22.2558}ADPg + {22.2558}Glc6Pg
  (HXKgHXKgVmax*ATPg*(1.-(ADPg*Glc6Pg)/(HXKgHXKgKeq*ATPg*Glcg))*Glcg)/(cytosol*HXKgHXKgKmATP*HXKgHXKgKmGlc*(1.+ADPg/HXKgHXKgKmADP+ATPg/HXKgHXKgKmATP)*(1.+Glc6Pg/HXKgHXKgKmGlc6P+Glcg/HXKgHXKgKmGlc))
PFKg:
 {22.2558}ATPg + {22.2558}Fru6Pg = {22.2558}ADPg + {22.2558}Fru16BPg
  (PFKgPFKgKi1*PFKgPFKgVmax*ATPg*(1.-(ADPg*Fru16BPg)/(PFKgPFKgKeq*ATPg*Fru6Pg))*Fru6Pg)/(cytosol*PFKgPFKgKmATP*PFKgPFKgKmFru6P*(PFKgPFKgKi1+Fru16BPg)*(PFKgPFKgKsATP/PFKgPFKgKmATP+ADPg/PFKgPFKgKmADP+ATPg/PFKgPFKgKmATP+(ADPg*Fru16BPg)/(PFKgPFKgKi2*PFKgPFKgKmADP)+Fru6Pg/PFKgPFKgKmFru6P+(ATPg*Fru6Pg)/(PFKgPFKgKmATP*PFKgPFKgKmFru6P)))
PGA3Tg:
 {22.2558}PGA3g = {1.0}PGA3c
  (-(PGA3TgPGA3Tgk*PGA3c)+PGA3TgPGA3Tgk*PGA3g)/cytosol
PGAMc:
 {1.0}PGA3c = {1.0}PGA2c
  (PGAMcPGAMcVmax*(1-PGA2c/(PGAMcPGAMcKeq*PGA3c))*PGA3c)/(cytosol*PGAMcPGAMcKmPGA3*(1.+PGA2c/PGAMcPGAMcKmPGA2+PGA3c/PGAMcPGAMcKmPGA3))
PGIg:
 {22.2558}Glc6Pg = {22.2558}Fru6Pg
  (PGIgPGIgVmax*(1-Fru6Pg/(PGIgPGIgKeq*Glc6Pg))*Glc6Pg)/(cytosol*PGIgPGIgKmGlc6P*(1.+Fru6Pg/PGIgPGIgKmFru6P+Glc6Pg/PGIgPGIgKmGlc6P))
PGKg:
 {22.2558}BPGA13g + {22.2558}ADPg = {22.2558}PGA3g + {22.2558}ATPg
  (PGKgPGKgVmax*ADPg*BPGA13g*(1.-(ATPg*PGA3g)/(PGKgPGKgKeq*ADPg*BPGA13g)))/(cytosol*PGKgPGKgKmADP*PGKgPGKgKmBPGA13*(1.+ADPg/PGKgPGKgKmADP+ATPg/PGKgPGKgKmATP)*(1.+BPGA13g/PGKgPGKgKmBPGA13+PGA3g/PGKgPGKgKmPGA3))
PYKc:
 {1.0}ADPc + {1.0}PEPc = {1.0}ATPc + {1.0}Pyrc
  (PYKcPYKcVmax*ADPc*(PEPc/(PYKcPYKcKmPEP*(1.+ADPc/PYKcPYKcKiADP+ATPc/PYKcPYKcKiATP)))**PYKcPYKcn*(1.-(ATPc*Pyrc)/(PYKcPYKcKeq*ADPc*PEPc)))/(cytosol*PYKcPYKcKmADP*(1.+ADPc/PYKcPYKcKmADP+ATPc/PYKcPYKcKmATP)*(1.+(PEPc/(PYKcPYKcKmPEP*(1.+ADPc/PYKcPYKcKiADP+ATPc/PYKcPYKcKiATP)))**PYKcPYKcn+Pyrc/PYKcPYKcKmPyr))
PyrTc:
 {1.0}Pyrc = {1.0}Pyre
  (PyrTcPyrTcVmax*Pyrc)/(cytosol*PyrTcPyrTcKmPyr*(1.+Pyrc/PyrTcPyrTcKmPyr))
TPIg:
 {22.2558}DHAPg = {22.2558}GA3Pg
  (TPIgTPIgVmax*DHAPg*(1-GA3Pg/(TPIgTPIgKeq*DHAPg)))/(cytosol*TPIgTPIgKmDHAP*(1.+DHAPg/TPIgTPIgKmDHAP+GA3Pg/TPIgTPIgKmGA3P))


#parameters
AKcAKck1 = 442.0
AKcAKck2 = 1000.0
AKgAKgk1 = 442.0
AKgAKgk2 = 1000.0
ALDgALDgKeq = 0.084
ALDgALDgKiADP = 1.51
ALDgALDgKiAMP = 3.65
ALDgALDgKiATP = 0.68
ALDgALDgKiGA3P = 0.098
ALDgALDgKmDHAP = 0.015
ALDgALDgKmFru16BP = 0.009
ALDgALDgKmGA3P = 0.067
ALDgALDgVmax = 560.0
ATPucATPuck = 50.0
DHAPtgDHAPtgk = 1000.0
ENOcENOcKeq = 4.12
ENOcENOcKmPEP = 0.24
ENOcENOcKmPGA2 = 0.054
ENOcENOcVmax = 598.0
EXTERNAL = 0.0
G3PDHgG3PDHgKeq = 17085.0
G3PDHgG3PDHgKmDHAP = 0.1
G3PDHgG3PDHgKmGly3P = 2.0
G3PDHgG3PDHgKmNAD = 0.4
G3PDHgG3PDHgKmNADH = 0.01
G3PDHgG3PDHgVmax = 465.0
GA3PtgGA3Ptgk = 1000.0
GAPDHgGAPDHgKeq = 0.066
GAPDHgGAPDHgKmBPGA13 = 0.1
GAPDHgGAPDHgKmGA3P = 0.15
GAPDHgGAPDHgKmNAD = 0.45
GAPDHgGAPDHgKmNADH = 0.02
GAPDHgGAPDHgVmax = 720.9
GKgGKgKeq = 0.000837
GKgGKgKmADP = 0.56
GKgGKgKmATP = 0.24
GKgGKgKmGly = 0.44
GKgGKgKmGly3P = 3.83
GKgGKgVmax = 200.0
GPOcGPOcKiSHAM = 0.021
GPOcGPOcKmGly3P = 1.7
GPOcGPOcVmax = 368.0
GlcTcGlcTcKmGlc = 1.1
GlcTcGlcTcVmax = 111.7
GlcTcGlcTcalpha = 0.75
GlcTgGlcTgk = 250000.0
Gly3PtgGly3Ptgk = 1000.0
GlyTcGlyTcKmGlye = 0.17
GlyTcGlyTcVrmax = 85.0
GlyTcGlyTck = 8.5
GlyTcGlyTcx = 1.0
GlyTcGlyTcy = 1.0
GlytgGlytgk = 1000.0
HXKgHXKgKeq = 759.0
HXKgHXKgKmADP = 0.126
HXKgHXKgKmATP = 0.116
HXKgHXKgKmGlc = 0.1
HXKgHXKgKmGlc6P = 12.0
HXKgHXKgVmax = 1929.0
O2c = 1.0
PFKgPFKgKeq = 1035.0
PFKgPFKgKi1 = 15.8
PFKgPFKgKi2 = 10.7
PFKgPFKgKmADP = 1.0
PFKgPFKgKmATP = 0.0648
PFKgPFKgKmFru6P = 0.999
PFKgPFKgKsATP = 0.0393
PFKgPFKgVmax = 1708.0
PGA3TgPGA3Tgk = 250.0
PGAMcPGAMcKeq = 0.17
PGAMcPGAMcKmPGA2 = 0.16
PGAMcPGAMcKmPGA3 = 0.15
PGAMcPGAMcVmax = 225.0
PGIgPGIgKeq = 0.46
PGIgPGIgKmFru6P = 0.12
PGIgPGIgKmGlc6P = 0.4
PGIgPGIgVmax = 1305.0
PGKgPGKgKeq = 3376.0
PGKgPGKgKmADP = 0.1
PGKgPGKgKmATP = 0.29
PGKgPGKgKmBPGA13 = 0.003
PGKgPGKgKmPGA3 = 1.62
PGKgPGKgVmax = 2862.0
PYKcPYKcKeq = 10800.0
PYKcPYKcKiADP = 0.64
PYKcPYKcKiATP = 0.57
PYKcPYKcKmADP = 0.114
PYKcPYKcKmATP = 15.0
PYKcPYKcKmPEP = 0.34
PYKcPYKcKmPyr = 50.0
PYKcPYKcVmax = 1020.0
PYKcPYKcn = 2.5
PyrTcPyrTcKmPyr = 1.96
PyrTcPyrTcVmax = 230.0
SHAM = 0.0
TPIgTPIgKeq = 0.046
TPIgTPIgKmDHAP = 1.2
TPIgTPIgKmGA3P = 0.25
TPIgTPIgVmax = 999.3
cytosol = 5.4549
default = 1.0
glycosome = 0.2451
Glce = 5.0
Glye = 1e-06
Pig = 0.0
Pyre = 0.0
default_compartment = 1.0


#initial values
ADPc = 1.0
ADPg = 1.0
AMPc = 0.1
AMPg = 0.1
ATPc = 4.9
ATPg = 4.9
BPGA13g = 0.4
DHAPc = 4.6
DHAPg = 4.6
Fru16BPg = 13.0
Fru6Pg = 0.2
GA3Pc = 0.01
GA3Pg = 0.14
Glc6Pg = 0.8
Glcc = 0.01
Glcg = 0.01
Gly3Pc = 1.5
Gly3Pg = 1.5
Glyc = 1e-06
Glyg = 1e-06
NADHg = 0.1
NADg = 3.9
PEPc = 1.4
PGA2c = 0.5
PGA3c = 17.0
PGA3g = 17.0
Pyrc = 14.0


#assignment rules