X13 X14 cytoplasm k1 X1 W cytoplasm k10 X9 cytoplasm k11 X10 cytoplasm V12 nucleus k13 X11 nucleus k14 k21 X11 X14 cytoplasm k15 X12 nucleus k_plus16 X11 X13 k_minus16 X14 cytoplasm k_plus17 X7 X11 k_minus17 X15 cytoplasm Vmax1 X16 W Km1 X16 Ki Ki X23 cytoplasm Vmax2 X17 Km2 X17 cytoplasm k2 X2 cytoplasm kcat1 X17 X18 Km3 X18 cytoplasm Vmax3 X19 Km4 X19 cytoplasm kcat2 X19 X20 Km5 X20 cytoplasm Vmax4 X21 Km6 X21 cytoplasm kcat3 X21 X22 Km7 X22 cytoplasm Vmax5 X23 Km8 X23 cytoplasm kcat4 X23 X24 Km9 X24 cytoplasm k18 X18 X25 k19 X24 cytoplasm Vmax6 X26 Km10 X26 cytoplasm kcat5 X14 n1 Km11 n1 X14 n1 cytoplasm k3 X2 X4 cytoplasm k20 X27 cytoplasm kcat6 X27 X18 Km12 X18 cytoplasm kcat7 X23 X5 Km13 X5 cytoplasm Vmax7 X28 Km14 X28 cytoplasm k4 X4 cytoplasm k5 X3 cytoplasm k_plus6 X5 X6 k_minus6 X4 cytoplasm k_plus7 X7 X12 k_minus7 X6 cytoplasm k_plus8 X3 X11 k_minus8 X8 cytoplasm k9 X8

The two events are used to increase the value of wnt from 0 to 1 between time t=500minutes and t=1000minutes.

 time 500 time 1000 1 time 1000 0