$\mathrm{Vm1}-\mathrm{Ki1G6P}\mathrm{G6P}$ $\frac{\mathrm{Vm2}}{1+\frac{\mathrm{Km2Glc}}{\mathrm{Glci}}+\frac{\mathrm{Km2ATP}}{\mathrm{ATP}}+\frac{\mathrm{Ks2Glc}\mathrm{Km2ATP}}{\mathrm{Glci}\mathrm{ATP}}}$ $\frac{\frac{1.1\mathrm{Vm3}\mathrm{G6P}^{\mathrm{n3}}}{\mathrm{K3Gly}^{\mathrm{n3}}+\mathrm{G6P}^{\mathrm{n3}}}}{1+\frac{\mathrm{Km30}}{0.7}(1+\frac{\mathrm{Km3G6P}}{\mathrm{G6P}})}$ $\frac{\frac{\frac{\mathrm{Vm4}\mathrm{g4R}\times 0.3\mathrm{G6P}}{\mathrm{K4F6P}}\mathrm{ATP}}{\mathrm{K4ATP}}(1+\frac{0.3\mathrm{G6P}}{\mathrm{K4F6P}}+\frac{\mathrm{ATP}}{\mathrm{K4ATP}}+\frac{\frac{\mathrm{g4R}\times 0.3\mathrm{G6P}}{\mathrm{K4F6P}}\mathrm{ATP}}{\mathrm{K4ATP}})}{(1+\frac{0.3\mathrm{G6P}}{\mathrm{K4F6P}}+\frac{\mathrm{ATP}}{\mathrm{K4ATP}}+\frac{\frac{\mathrm{g4R}\times 0.3\mathrm{G6P}}{\mathrm{K4F6P}}\mathrm{ATP}}{\mathrm{K4ATP}})^2+\mathrm{L40}\left(\frac{1+\frac{\mathrm{c4AMP}(3-\mathrm{ATP}-0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5}))}{\mathrm{K4AMP}}}{1+\frac{3-\mathrm{ATP}-0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K4AMP}}}\right)^2(1+\frac{\mathrm{c4F6P}\times 0.3\mathrm{G6P}}{\mathrm{K4F6P}}+\frac{\mathrm{c4ATP}\mathrm{ATP}}{\mathrm{K4ATP}}+\frac{\frac{\mathrm{gT}\mathrm{c4F6P}\times 0.3\mathrm{G6P}}{\mathrm{K4F6P}}\mathrm{c4ATP}\mathrm{ATP}}{\mathrm{K4ATP}})^2}$ $\frac{\frac{\frac{\mathrm{Vm7}\mathrm{PEP}}{\mathrm{K6PEP}}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}(\mathrm{g6R}(1+\frac{\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6R}\mathrm{PEP}}{\mathrm{K6PEP}}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}})+\frac{\frac{\mathrm{q6}\mathrm{L60}\left(\frac{1+\frac{\mathrm{c6FDP}\mathrm{FDP}}{\mathrm{K6FDP}}}{1+\frac{\mathrm{FDP}}{\mathrm{K6FDP}}}\right)^2\mathrm{g6T}\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}(1+\frac{\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6T}\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}))}{(1+\frac{9.5510^{-9}}{\mathrm{h6}})((1+\frac{\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6R}\mathrm{PEP}}{\mathrm{K6PEP}}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}})^2+\mathrm{L60}\left(\frac{1+\frac{\mathrm{c6FDP}\mathrm{FDP}}{\mathrm{K6FDP}}}{1+\frac{\mathrm{FDP}}{\mathrm{K6FDP}}}\right)^2(1+\frac{\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6T}\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}})^2)}$ $\frac{\mathrm{Vm5}}{1+\frac{\mathrm{K5G3P}}{0.01\mathrm{FDP}}+(\frac{\mathrm{K5NAD}}{\mathrm{NAD}}+\frac{\mathrm{K5G3P}\mathrm{K5NAD}}{\mathrm{NAD}\times 0.01\mathrm{FDP}}+\frac{\mathrm{K5G3P}\mathrm{K5NAD}\mathrm{NADH}}{\mathrm{NAD}\times 0.01\mathrm{FDP}\mathrm{K5NADH}})(1+\frac{0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K5ADP}}+\frac{3-\mathrm{ATP}-0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K5AMP}}+\frac{\mathrm{ATP}}{\mathrm{K5ATP}})}$ $\frac{\frac{\frac{\mathrm{Vm6}\mathrm{PEP}}{\mathrm{K6PEP}}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}(\mathrm{g6R}(1+\frac{\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6R}\mathrm{PEP}}{\mathrm{K6PEP}}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}})+\frac{\frac{\mathrm{q6}\mathrm{L60}\left(\frac{1+\frac{\mathrm{c6FDP}\mathrm{FDP}}{\mathrm{K6FDP}}}{1+\frac{\mathrm{FDP}}{\mathrm{K6FDP}}}\right)^2\mathrm{g6T}\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}(1+\frac{\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6T}\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}))}{(1+\frac{9.5510^{-9}}{\mathrm{h6}})((1+\frac{\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6R}\mathrm{PEP}}{\mathrm{K6PEP}}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}})^2+\mathrm{L60}\left(\frac{1+\frac{\mathrm{c6FDP}\mathrm{FDP}}{\mathrm{K6FDP}}}{1+\frac{\mathrm{FDP}}{\mathrm{K6FDP}}}\right)^2(1+\frac{\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}+\frac{\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}}+\frac{\frac{\mathrm{g6T}\mathrm{c6PEP}\mathrm{PEP}}{\mathrm{K6PEP}}\mathrm{c6ADP}\times 0.5(-\mathrm{ATP}+(12\mathrm{ATP}-3\mathrm{ATP}^2)^{0.5})}{\mathrm{K6ADP}})^2)}$ $\mathrm{Vm8}\mathrm{ATP}$