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Multidrug Therapy for HIV Infection: Dynamics of Immune System.

  • Deepmala Kamboj
  • MD Sharma
Acta Biotheor. 2019; 67 (2): 129
Abstract
A mathematical model of the dynamics of the immune system is considered to illustrate the effect of its response to HIV infection, i.e. on viral growth and on T-cell dynamics. The specific immune response is measured by the levels of cytotoxic lymphocytes in a human body. The existence and stability analyses are performed for infected steady state and uninfected steady state. In order to keep infection under control, roles of drug therapies are analyzed in the presence of efficient immune response. Numerical simulations are computed and exhibited to illustrate the support of the immune system to drug therapies, so as to ensure the decay of infection and to maintain the level of healthy cells.
Id Name JWS model
model8a_kamboj1 model8a_kamboj1 kamboj1
model8b_kamboj1 model8b_kamboj1 kamboj1
model8c_kamboj1 model8c_kamboj1 kamboj1
model8d_kamboj1 model8d_kamboj1 kamboj1
Id Name Source Number of Data Sources
Id Name Model Simulation Simulation Simulation
task8a_model8a_kamboj1 task8a_model8a_kamboj1 model8a_kamboj1 0.0 500.0 1000
task8c_model8c_kamboj1 task8c_model8c_kamboj1 model8c_kamboj1 0.0 500.0 1000
task8d_model8d_kamboj1 task8d_model8d_kamboj1 model8d_kamboj1 0.0 500.0 1000
task8b_model8b_kamboj1 task8b_model8b_kamboj1 model8b_kamboj1 0.0 500.0 1000

2D Plots

Id Name Number of Curves
kamboj8a Fig 8a - T-cell population 0
kamboj8b Fig 8b - Viral load 0
kamboj8c Fig 8c - Immune cell population/ CTLs (CD8) 0

CSV Reports

Id Name Number of Columns