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ho1995_Fig3

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Model Manuscripts

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection.

  • DD Ho
  • AU Neumann
  • Alan S Perelson
  • W Chen
  • JM Leonard
  • M Markowitz
Nature 1995; 373 (6510): 123-126
Abstract
Treatment of infected patients with ABT-538, an inhibitor of the protease of human immunodeficiency virus type 1 (HIV-1), causes plasma HIV-1 levels to decrease exponentially (mean half-life, 2.1 +/- 0.4 days) and CD4 lymphocyte counts to rise substantially. Minimum estimates of HIV-1 production and clearance and of CD4 lymphocyte turnover indicate that replication of HIV-1 in vivo is continuous and highly productive, driving the rapid turnover of CD4 lymphocytes.
Id Name JWS model
model0_ho1 ho1 ho1
model2_ho1 ho1 ho1
model1_ho1 ho1 ho1
Id Name Source Number of Data Sources
Id Name Model Simulation Simulation Simulation
task0_model0_ho1 ho1 0.0 30.0 1000
task1_model1_ho1 ho1 0.0 30.0 1000
task2_model2_ho1 ho1 0.0 30.0 1000

2D Plots

Id Name Number of Curves
Figure3_Top_patient303 Figure 3 Top Patient 303 0
Figure3_Top_patient403 Figure 3 Top Patient 403 0
Figure3_Top_patient409 Figure 3 Top Patient 409 0

CSV Reports

Id Name Number of Columns