JWS Online

dutoit1

Detail

Download

Reactions

vPFvALD

f16bpPF = dhapPF + gapPF

vPFvATPASE

atpPF = adpPF

vPFvENO

p2gPF = pepPF

vPFvG3PDH

dhapPF + nadhPF = g3pPF + nadPF

vPFvGAPDH

gapPF + nadPF = b13pgPF + nadhPF

vPFvGLCtr

glcRBCi = glcPF

vPFvGLYtr

g3pPF = glyEXT

vPFvHK

atpPF + glcPF = adpPF + g6pPF

vPFvLACtr

lacPF = lacRBCi

vPFvLDH

nadhPF + pyrPF = lacPF + nadPF

vPFvPFK

atpPF + f6pPF = adpPF + f16bpPF

vPFvPGI

g6pPF = f6pPF

vPFvPGK

adpPF + b13pgPF = atpPF + p3gPF

vPFvPGM

p3gPF = p2gPF

vPFvPK

adpPF + pepPF = atpPF + pyrPF

vPFvPYRtr

pyrPF = pyrRBCi

vPFvTPI

dhapPF = gapPF

vRBCivAK

adpRBCi + mgadpRBCi = ampRBCi + mgatpRBCi

vRBCivALD

f16p2RBCi = dhapRBCi + gapRBCi

vRBCivATPASE

mgatpRBCi = mgadpRBCi + phosRBCi

vRBCivBPGSP1

b13pgRBCi + bpgspRBCi = bpgspb13pgRBCi

vRBCivBPGSP2

bpgspb13pgRBCi = bpgsppRBCi + p3gRBCi

vRBCivBPGSP3

bpgsppRBCi + p3gRBCi = bpgsppp3gRBCi

vRBCivBPGSP4

bpgsppRBCi + p2gRBCi = bpgsppp2gRBCi

vRBCivBPGSP5

bpgsppp3gRBCi = bpgspb23pgRBCi

vRBCivBPGSP6

bpgsppp2gRBCi = bpgspb23pgRBCi

vRBCivBPGSP7

bpgspb23pgRBCi = b23pgRBCi + bpgspRBCi

vRBCivBPGSP8

bpgsppRBCi + phosRBCi = bpgsppphosRBCi

vRBCivBPGSP9

bpgsppphosRBCi = bpgspRBCi + {2.0}phosRBCi

vRBCivENO

p2gRBCi = pepRBCi

vRBCivG6PDH

g6pRBCi + nadpRBCi = nadphRBCi + p6glRBCi

vRBCivGAPDH

gapRBCi + nadRBCi + phosRBCi = b13pgRBCi + nadhRBCi

vRBCivGLCTRANSPORT

glcEXT = glcRBCi

vRBCivGSSGR

gssgRBCi + nadphRBCi = {2.0}gshRBCi + nadpRBCi

vRBCivHBADP

adpRBCi + hbRBCi = hbadpRBCi

vRBCivHBATP

atpRBCi + hbRBCi = hbatpRBCi

vRBCivHBB13PG

b13pgRBCi + hbRBCi = hbb13pgRBCi

vRBCivHBB23PG

b23pgRBCi + hbRBCi = hbb23pgRBCi

vRBCivHBMGATP

hbRBCi + mgatpRBCi = hbmgatpRBCi

vRBCivHK

glcRBCi + mgatpRBCi = g6pRBCi + mgadpRBCi

vRBCivLACTRANSPORT

lacRBCi = lacEXT

vRBCivLDH

nadhRBCi + pyrRBCi = lacRBCi + nadRBCi

vRBCivLDHP

nadphRBCi + pyrRBCi = lacRBCi + nadpRBCi

vRBCivMGADP

adpRBCi + mgRBCi = mgadpRBCi

vRBCivMGATP

mgRBCi + atpRBCi = mgatpRBCi

vRBCivMGB13PG

b13pgRBCi + mgRBCi = mgb13pgRBCi

vRBCivMGB23PG

b23pgRBCi + mgRBCi = mgb23pgRBCi

vRBCivMGF16P2

f16p2RBCi + mgRBCi = mgf16p2RBCi

vRBCivMGG16P2

g16p2RBCi + mgRBCi = mgg16p2RBCi

vRBCivMGPHOS

mgRBCi + phosRBCi = mgphosRBCi

vRBCivOX

{2.0}gshRBCi = gssgRBCi

vRBCivOXNADH

nadhRBCi = nadRBCi

vRBCivP6GDH

nadpRBCi + p6gRBCi = nadphRBCi + ru5pRBCi

vRBCivPFK

f6pRBCi + mgatpRBCi = f16p2RBCi + mgadpRBCi

vRBCivPGI

g6pRBCi = f6pRBCi

vRBCivPGK

b13pgRBCi + mgadpRBCi = mgatpRBCi + p3gRBCi

vRBCivPGLHYDROLYSIS

p6glRBCi = p6gRBCi

vRBCivPGM

p3gRBCi = p2gRBCi

vRBCivPHOSTRANSPORT

phosRBCi = phosEXT

vRBCivPK

mgadpRBCi + pepRBCi = mgatpRBCi + pyrRBCi

vRBCivPYRTRANSPORT

pyrRBCi = pyrEXT

vRBCivR5PI

ru5pRBCi = rib5pRBCi

vRBCivRu5PE

ru5pRBCi = xu5pRBCi

vRBCivTA

gapRBCi + sed7pRBCi = ery4pRBCi + f6pRBCi

vRBCivTIM

gapRBCi = dhapRBCi

vRBCivTK1

tkRBCi + xu5pRBCi = tkxu5pRBCi

vRBCivTK2

tkxu5pRBCi = gapRBCi + tkgRBCi

vRBCivTK3

rib5pRBCi + tkgRBCi = tkgrib5pRBCi

vRBCivTK4

tkgrib5pRBCi = sed7pRBCi + tkRBCi

vRBCivTK5

ery4pRBCi + tkgRBCi = tkgery4pRBCi

vRBCivTK6

tkgery4pRBCi = f6pRBCi + tkRBCi

Parameters

Global parameters

CRBCvMGADP*

CRBCvMGATP*

CRBCvMGB13PG*

CRBCvMGB23PG*

CRBCvMGF16P2*

CRBCvMGG16P2*

CRBCvMGPHOS*

ConcADPRBC*

ConcAMPRBC*

ConcATPRBC*

ConcAdpPF*

ConcAtpPF*

ConcB13PGRBC*

ConcB13pgPF*

ConcB23PGRBC*

ConcBPGSPB13PGRBC*

ConcBPGSPB23PGRBC*

ConcBPGSPPP2GRBC*

ConcBPGSPPP3GRBC*

ConcBPGSPPRBC*

ConcBPGSPRBC*

ConcBpgsppphosRBC*

ConcCo2RBC*

ConcDhapPF*

ConcDhapRBC*

ConcEry4PRBC*

ConcF16P2RBC*

ConcF16bpPF*

ConcF6PRBC*

ConcF6pPF*

ConcG16P2RBC*

ConcG6PRBC*

ConcG6pPF*

ConcGSHRBC*

ConcGapPF*

ConcGapRBC*

ConcGlcEXT*

ConcGlcPF*

ConcGlcRBC*

ConcGly3pPF*

ConcGlyEXT*

ConcGssgRBC*

ConcHbADPRBC*

ConcHbATPRBC*

ConcHbB13PGRBC*

ConcHbB23PGRBC*

ConcHbRBC*

ConcHbmgatpRBC*

ConcLacEXT*

ConcLacPF*

ConcLacRBC*

ConcMgADPRBC*

ConcMgB13PGRBC*

ConcMgB23PGRBC*

ConcMgF16P2RBC*

ConcMgRBC*

ConcMgatpRBC*

ConcMgg16p2RBC*

ConcMgphosRBC*

ConcNADPRBC*

ConcNADRBC*

ConcNadPF*

ConcNadhPF*

ConcNadhRBC*

ConcNadphRBC*

ConcP2GARBC*

ConcP2gPF*

ConcP3GARBC*

ConcP3gPF*

ConcP6GLRBC*

ConcP6GRBC*

ConcPEPRBC*

ConcPepPF*

ConcPhosEXT*

ConcPhosRBC*

ConcPyrEXT*

ConcPyrPF*

ConcPyrRBC*

ConcRib5PRBC*

ConcRu5PRBC*

ConcSed7PRBC*

ConcTKGEry4PRBC*

ConcTKGRBC*

ConcTKGRib5PRBC*

ConcTKRBC*

ConcTkxu5pRBC*

ConcXu5PRBC*

ERBCvHK*

ERBCvPGI*

K10RBCvBPGSP6*

K10RBCvG6PDH*

K10RBCvGSSGR*

K10RBCvP6GDH*

K10RBCvTK5*

K11RBCvBPGSP6*

K11RBCvGSSGR*

K11RBCvP6GDH*

K11RBCvTK6*

K12RBCvBPGSP7*

K12RBCvGSSGR*

K12RBCvP6GDH*

K12RBCvTK6*

K13RBCvBPGSP7*

K14RBCvBPGSP8*

K15RBCvBPGSP8*

K16RBCvBPGSP9*

K1RBCvAK*

K1RBCvBPGSP1*

K1RBCvG6PDH*

K1RBCvGSSGR*

K1RBCvP6GDH*

K1RBCvR5PI*

K1RBCvRu5PE*

K1RBCvTA*

K1RBCvTK1*

K2RBCvAK*

K2RBCvBPGSP1*

K2RBCvG6PDH*

K2RBCvGSSGR*

K2RBCvP6GDH*

K2RBCvR5PI*

K2RBCvRu5PE*

K2RBCvTA*

K2RBCvTK1*

K3RBCvBPGSP2*

K3RBCvG6PDH*

K3RBCvGSSGR*

K3RBCvP6GDH*

K3RBCvR5PI*

K3RBCvRu5PE*

K3RBCvTA*

K3RBCvTK2*

K4RBCvBPGSP3*

K4RBCvG6PDH*

K4RBCvGSSGR*

K4RBCvP6GDH*

K4RBCvR5PI*

K4RBCvRu5PE*

K4RBCvTA*

K4RBCvTK2*

K5RBCvBPGSP3*

K5RBCvG6PDH*

K5RBCvGSSGR*

K5RBCvP6GDH*

K5RBCvTA*

K5RBCvTK3*

K6RBCvBPGSP4*

K6RBCvG6PDH*

K6RBCvGSSGR*

K6RBCvP6GDH*

K6RBCvTA*

K6RBCvTK3*

K7RBCvBPGSP4*

K7RBCvG6PDH*

K7RBCvGSSGR*

K7RBCvP6GDH*

K7RBCvTA*

K7RBCvTK4*

K8RBCvBPGSP5*

K8RBCvG6PDH*

K8RBCvGSSGR*

K8RBCvP6GDH*

K8RBCvTA*

K8RBCvTK4*

K9RBCvBPGSP5*

K9RBCvG6PDH*

K9RBCvGSSGR*

K9RBCvP6GDH*

K9RBCvTK5*

KRBCvATPASE*

KRBCvMGADP*

KRBCvMGATP*

KRBCvMGB13PG*

KRBCvMGB23PG*

KRBCvMGF16P2*

KRBCvMGG16P2*

KRBCvOX*

KRBCvOXNADH*

KaRBCvHBADP*

KaRBCvHBATP*

KaRBCvHBB13PG*

KaRBCvHBBPG*

KaRBCvHBMGATP*

KaRBCvMGADP*

KaRBCvMGATP*

KaRBCvMGB13PG*

KaRBCvMGB23PG*

KaRBCvMGF16P2*

KaRBCvMGG16P2*

KaRBCvMGPHOS*

KaRBCvPFK*

KadpPFvHK*

KadpPFvPFK*

KadpPFvPGK*

KadpPFvPK*

KahbRBC*

KatpPFvHK*

KatpPFvPFK*

KatpPFvPGK*

Kb13pgPFvGAPDH*

Kb13pgPFvPGK*

KcatfRBCvALD*

KcatfRBCvENO*

KcatfRBCvGAPDH*

KcatfRBCvHK*

KcatfRBCvLDH*

KcatfRBCvPFK*

KcatfRBCvPGI*

KcatfRBCvPGK*

KcatfRBCvPGM*

KcatfRBCvPK*

KcatfRBCvTIM*

KcatrRBCvALD*

KcatrRBCvENO*

KcatrRBCvGAPDH*

KcatrRBCvHK*

KcatrRBCvLDH*

KcatrRBCvPFK*

KcatrRBCvPGI*

KcatrRBCvPGK*

KcatrRBCvPGM*

KcatrRBCvPK*

KcatrRBCvTIM*

KdPFvLACtr*

KdPFvPYRtr*

KdRBCvHBADP*

KdRBCvHBATP*

KdRBCvHBB13PG*

KdRBCvHBBPG*

KdRBCvHBMGATP*

KdRBCvMGADP*

KdRBCvMGATP*

KdRBCvMGB13PG*

KdRBCvMGB23PG*

KdRBCvMGF16P2*

KdRBCvMGG16P2*

KdRBCvMGPHOS*

KdhapPFvALD*

KdhapPFvG3PDH*

KdhapPFvTPI*

KdibpgRBCvHK*

Kdig16p2RBCvHK*

Kdig6pRBCvHK*

KdigshRBCvHK*

KeqPFvALD*

KeqPFvENO*

KeqPFvG3PDH*

KeqPFvHK*

KeqPFvPGI*

KeqPFvPGK*

KeqPFvPGM*

KeqPFvTPI*

Kf16bpPFvALD*

Kf16bpPFvPFK*

Kf6pPFvPFK*

Kf6pPFvPGI*

KfRBCvLDHP*

Kg3pPFvG3PDH*

Kg6pPFvHK*

Kg6pPFvPGI*

KgapPFvALD*

KgapPFvGAPDH*

KgapPFvTPI*

KglcPFvHK*

Kh2bpgRBCvMGB13PG*

Kh2bpgRBCvMGB23PG*

Kh2fRBCvMGF16P2*

Kh2fRBCvMGG16P2*

KhadpRBCvAK*

KhadpRBCvMGADP*

KhampRBCvAK*

KhatpRBCvMGATP*

KhbpgRBCvMGB13PG*

KhbpgRBCvMGB23PG*

KhfRBCvMGF16P2*

KhfRBCvMGG16P2*

KhphosRBCvMGPHOS*

KhydrolRBCvPGLHYDROLYSIS*

KiRBCvLACTRANSPORT*

KiRBCvPHOSTRANSPORT*

KiRBCvPYRTRANSPORT*

KiadpPFvPK*

KiatpPFvHK*

KiatpPFvPK*

Kib13pgRBCvGAPDH*

Kib13pgRBCvPGK*

Kib23pgRBCvALD*

Kidb13pgRBCvGAPDH*

KidgapRBCvGAPDH*

KidhapRBCvALD*

KidpyrRBCvLDH*

Kif16p2RBCvALD*

Kig6pRBCvHK*

KigapRBCvGAPDH*

KiglcRBCvHK*

KilacPFvPYRtr*

KilacRBCvLDH*

KimgRBCvENO*

KimgadpRBCvHK*

KimgadpRBCvPGK*

KimgatpRBCvHK*

KimgatpRBCvPGK*

KinadRBCvGAPDH*

KinadRBCvLDH*

KinadhRBCvGAPDH*

KinadhRBCvLDH*

Kip2gRBCvENO*

Kip3gRBCvPGK*

KipepPFvPK*

KipepPFvTPI*

KipepRBCvENO*

KiphosRBCvGAPDH*

KipyrPFvLACtr*

KipyrPFvPK*

KipyrRBCvLDH*

KkadpRBCvAK*

KkadpRBCvMGADP*

KkampRBCvAK*

KkatpRBCvMGATP*

KkbpgRBCvMGB13PG*

KkbpgRBCvMGB23PG*

KkfRBCvMGF16P2*

KkfRBCvMGG16P2*

KkhbpgRBCvMGB13PG*

KkhbpgRBCvMGB23PG*

KkhfRBCvMGF16P2*

KkhfRBCvMGG16P2*

KkphosRBCvMGPHOS*

KlacPFvLACtr*

KlacPFvLDH*

Klactonase1RBCvPGLHYDROLYSIS*

Klactonase2RBCvPGLHYDROLYSIS*

Klactonase3RBCvPGLHYDROLYSIS*

KmPFvATPASE*

KmPFvGLCtr*

Kmb13pgRBCvGAPDH*

Kmb13pgRBCvPGK*

KmdhapRBCvALD*

KmdhapRBCvTIM*

Kmf16p2RBCvALD*

Kmf16p2RBCvPFK*

Kmf6pRBCvPFK*

Kmf6pRBCvPGI*

Kmg6pRBCvPGI*

KmgapRBCvALD*

KmgapRBCvGAPDH*

KmgapRBCvTIM*

KmghadpRBCvMGADP*

KmghatpRBCvMGATP*

KmghbpgRBCvMGB13PG*

KmghbpgRBCvMGB23PG*

KmghfRBCvMGF16P2*

KmghfRBCvMGG16P2*

KmlacRBCvLDH*

KmlacRBCvLDHP*

KmmgRBCvENO*

KmmgadpRBCvHK*

KmmgadpRBCvPFK*

KmmgadpRBCvPGK*

KmmgatpRBCvHK*

KmmgatpRBCvPFK*

KmmgatpRBCvPGK*

KmnadRBCvGAPDH*

KmnadRBCvLDH*

KmnadhRBCvGAPDH*

KmnadhRBCvLDH*

Kmp2gRBCvENO*

Kmp2gRBCvPGM*

Kmp3gRBCvPGK*

Kmp3gRBCvPGM*

KmpepRBCvENO*

KmphosRBCvGAPDH*

KmpyrRBCvLDH*

KmpyrRBCvLDHP*

KnadPFvG3PDH*

KnadPFvGAPDH*

KnadPFvLDH*

KnadhPFvG3PDH*

KnadhPFvGAPDH*

KnadhPFvLDH*

Kp2gPFvENO*

Kp2gPFvPGM*

Kp3gPFvPGK*

Kp3gPFvPGM*

KpepPFvENO*

KpepPFvPK*

KpyrPFvLDH*

KpyrPFvPYRtr*

KrRBCvLDHP*

KrampRBCvPFK*

Krf16p2RBCvPK*

Krg16p2RBCvPFK*

Krg16p2RBCvPK*

KrmgadpRBCvPK*

KrmgatpRBCvPK*

KrpepRBCvPK*

KrphosRBCvPFK*

KrpyrRBCvPK*

KtatpRBCvPFK*

KtatpRBCvPK*

Ktb23pgRBCvPFK*

KtmgRBCvPFK*

LPFvPK*

RtvRBC*

TsRBC*

VPFvALD*

VPFvATPASE*

VPFvENO*

VPFvGAPDH*

VPFvGLCtr*

VPFvHK*

VPFvLACtr*

VPFvPFK*

VPFvPGI*

VPFvPGM*

VPFvPK*

VPFvPYRtr*

VPFvTPI*

VRBCvALD*

VRBCvENO*

VRBCvG6PDH*

VRBCvGAPDH*

VRBCvGLCTRANSPORT*

VRBCvGSSGR*

VRBCvLDH*

VRBCvP6GDH*

VRBCvPFK*

VRBCvPGK*

VRBCvPGLHYDROLYSIS*

VRBCvPGM*

VRBCvPK*

VRBCvR5PI*

VRBCvRu5PE*

VRBCvTA*

VRBCvTIM*

VfPFvG3PDH*

VfPFvLDH*

VrPFvGAPDH*

VrPFvLDH*

VrPFvPGK*

alphaPFvGLCtr*

bpgxRBC*

cyt*

glcAlpha*

gssgxRBC*

hbxRBC*

kAlpha*

kBeta*

kPFvGLYtr*

kRBC*

ki1*

ki2*

nRBCvPFK*

nadpxRBC*

pHConversionFactor*

phPF*

phRBC*

pt*

tkxRBC*

xatpRBC*

xg16p2RBC*

xphosRBC*

Vpf*

Vrbci*

vBld*

Initial values

adpPF

adpRBCi

ampRBCi

atpPF

atpRBCi

b13pgPF

b13pgRBCi

b23pgRBCi

bpgspRBCi

bpgspb13pgRBCi

bpgspb23pgRBCi

bpgsppRBCi

bpgsppp2gRBCi

bpgsppp3gRBCi

bpgsppphosRBCi

dhapPF

dhapRBCi

ery4pRBCi

f16bpPF

f16p2RBCi

f6pPF

f6pRBCi

g16p2RBCi

g3pPF

g6pPF

g6pRBCi

gapPF

gapRBCi

glcPF

glcRBCi

gshRBCi

gssgRBCi

hbRBCi

hbadpRBCi

hbatpRBCi

hbb13pgRBCi

hbb23pgRBCi

hbmgatpRBCi

lacPF

lacRBCi

mgRBCi

mgadpRBCi

mgatpRBCi

mgb13pgRBCi

mgb23pgRBCi

mgf16p2RBCi

mgg16p2RBCi

mgphosRBCi

nadPF

nadRBCi

nadhPF

nadhRBCi

nadpRBCi

nadphRBCi

p2gPF

p2gRBCi

p3gPF

p3gRBCi

p6gRBCi

p6glRBCi

pepPF

pepRBCi

phosRBCi

pyrPF

pyrRBCi

rib5pRBCi

ru5pRBCi

sed7pRBCi

tkRBCi

tkgRBCi

tkgery4pRBCi

tkgrib5pRBCi

tkxu5pRBCi

xu5pRBCi

LRBCvPK = 1.58489319246111 * pow(10.0, -7.0) * pHConversionFactor * pow(1.0 + atpRBCi / (KtatpRBCvPK * Vrbci), 4.0) / (hRBC * pow(1.0 + f16p2RBCi / (Krf16p2RBCvPK * Vrbci) + g16p2RBCi / (Krg16p2RBCvPK * Vrbci), 4.0) * pow(1.0 + pepRBCi / (KrpepRBCvPK * Vrbci) + pyrRBCi / (KrpyrRBCvPK * Vrbci), 4.0))

KiapppyrRBCvLDH = 0.284747248950801 * (1.0 + 1.58489319246111 * pow(10.0, -7.0) * pow(10.0, phRBC)) * KipyrRBCvLDH

KiapplacRBCvLDH = 0.715252751049199 * (1.0 + 6.30957344480193 * pow(10.0, 6.0) / pow(10.0, phRBC)) * KilacRBCvLDH

KcatfappRBCvGAPDH = KcatfRBCvGAPDH / (1.0 + pow(10.0, -10.0 + phRBC) + 3.16227766016838 * pow(10.0, 7.0) / pow(10.0, phRBC))

KaappRBCvMGF16P2 = CRBCvMGF16P2 * KaRBCvMGF16P2 * (hRBC * KhfRBCvMGF16P2 * KmghfRBCvMGF16P2 + KRBCvMGF16P2) / (1.0 + hRBC * KhfRBCvMGF16P2 + pow(hRBC, 2.0) * Kh2fRBCvMGF16P2 * KhfRBCvMGF16P2 + KkfRBCvMGF16P2 * kRBC + hRBC * KhfRBCvMGF16P2 * KkhfRBCvMGF16P2 * kRBC)

KaappRBCvMGG16P2 = CRBCvMGG16P2 * KaRBCvMGG16P2 * (hRBC * KhfRBCvMGG16P2 * KmghfRBCvMGG16P2 + KRBCvMGG16P2) / (1.0 + hRBC * KhfRBCvMGG16P2 + pow(hRBC, 2.0) * Kh2fRBCvMGG16P2 * KhfRBCvMGG16P2 + KkfRBCvMGG16P2 * kRBC + hRBC * KhfRBCvMGG16P2 * KkhfRBCvMGG16P2 * kRBC)

KeqRBCvPHOSTRANSPORT = (1.0 + pow(10.0, -6.75 + phRBC)) / (pow(10.0, -6.75 + phRBC) / pow(RtvRBC, 2.0) + pow(RtvRBC, -1.0))

K6appRBCvBPGSP4 = 1.75857757502918 * K6RBCvBPGSP4 / (1.0 + 4.78630092322638 * pow(10.0, 28.0) / pow(10.0, 4.0 * phRBC))

KiappgapRBCvGAPDH = KigapRBCvGAPDH / (1.0 + pow(10.0, -10.0 + phRBC) + 3.16227766016838 * pow(10.0, 7.0) / pow(10.0, phRBC))

glyEXT = ConcGlyEXT * vBld

KaappRBCvHBB13PG = HbpHRBC * KaRBCvHBB13PG

hPF = pHConversionFactor / pow(10.0, phPF)

KaappRBCvHBATP = HbpHRBC * KaRBCvHBATP

KaappRBCvHBMGATP = HbpHRBC * KaRBCvHBMGATP

KiappnadhRBCvGAPDH = 6.30957344480193 * pow(10.0, -8.0) * pow(10.0, phRBC) * KinadhRBCvGAPDH

trophToRBC = Vpf / Vrbci

lacEXT = ConcLacEXT * vBld

KaappRBCvHBADP = HbpHRBC * KaRBCvHBADP

KaappRBCvHBBPG = HbpHRBC * KaRBCvHBBPG

KcatrappRBCvHK = KcatrRBCvHK / (1.0 + 1.0471285480509 * pow(10.0, 7.0) / pow(10.0, phRBC) + 2.81838293126445 * pow(10.0, -10.0) * pow(10.0, phRBC))

K4appRBCvBPGSP3 = 1.75857757502918 * K4RBCvBPGSP3 / (1.0 + 4.78630092322638 * pow(10.0, 28.0) / pow(10.0, 4.0 * phRBC))

KaappRBCvMGADP = CRBCvMGADP * KaRBCvMGADP * (hRBC * KhadpRBCvMGADP * KmghadpRBCvMGADP + KRBCvMGADP) / (1.0 + hRBC * KhadpRBCvMGADP + KkadpRBCvMGADP * kRBC)

K2appRBCvAK = K2RBCvAK * (1.0 + hRBC * KhampRBCvAK + KkampRBCvAK * kRBC)

KmapplacRBCvLDH = 0.715252751049199 * (1.0 + 6.30957344480193 * pow(10.0, 6.0) / pow(10.0, phRBC)) * KmlacRBCvLDH

Kiappb13pgRBCvGAPDH = Kib13pgRBCvGAPDH / (1.0 + pow(10.0, -10.0 + phRBC) + 3.16227766016838 * pow(10.0, 7.0) / pow(10.0, phRBC))

KoRBCvPHOSTRANSPORT = KiRBCvPHOSTRANSPORT / KeqRBCvPHOSTRANSPORT

co2RBCi = ConcCo2RBC * Vrbci

phosEXT = ConcPhosEXT * vBld

KoRBCvPYRTRANSPORT = KiRBCvPYRTRANSPORT / RtvRBC

K13appRBCvBPGSP7 = 1.75857757502918 * K13RBCvBPGSP7 / (1.0 + 4.78630092322638 * pow(10.0, 28.0) / pow(10.0, 4.0 * phRBC))

KoRBCvLACTRANSPORT = KiRBCvLACTRANSPORT / KeqRBCvLACTRANSPORT

KmapppyrRBCvLDH = 0.284747248950801 * (1.0 + 1.58489319246111 * pow(10.0, -7.0) * pow(10.0, phRBC)) * KmpyrRBCvLDH

hRBC = pHConversionFactor / pow(10.0, phRBC)

glcEXT = ConcGlcEXT * vBld

pyrEXT = ConcPyrEXT * vBld

KmappnadhRBCvGAPDH = 6.30957344480193 * pow(10.0, -8.0) * pow(10.0, phRBC) * KmnadhRBCvGAPDH

KeqRBCvLACTRANSPORT = (1.0 + pow(10.0, -3.73 + phRBC)) / (1.0 + pow(10.0, -3.73 + phRBC) / RtvRBC)

K1appRBCvBPGSP1 = 3.51188643150958 * K1RBCvBPGSP1 / (1.0 + 1.58489319246111 * pow(10.0, -7.0) * pow(10.0, phRBC))

KcatfappRBCvHK = KcatfRBCvHK / (1.0 + 1.0471285480509 * pow(10.0, 7.0) / pow(10.0, phRBC) + 2.81838293126445 * pow(10.0, -10.0) * pow(10.0, phRBC))

KcatrappRBCvGAPDH = KcatrRBCvGAPDH / (1.0 + pow(10.0, -10.0 + phRBC) + 3.16227766016838 * pow(10.0, 7.0) / pow(10.0, phRBC))

KaappRBCvMGB23PG = CRBCvMGB23PG * KaRBCvMGB23PG * (hRBC * KhbpgRBCvMGB23PG * KmghbpgRBCvMGB23PG + KRBCvMGB23PG) / (1.0 + hRBC * KhbpgRBCvMGB23PG + pow(hRBC, 2.0) * Kh2bpgRBCvMGB23PG * KhbpgRBCvMGB23PG + KkbpgRBCvMGB23PG * kRBC + hRBC * KhbpgRBCvMGB23PG * KkhbpgRBCvMGB23PG * kRBC)

KaappRBCvMGPHOS = KaRBCvMGPHOS * (1.0 + KkphosRBCvMGPHOS * kRBC + 6.30957344480193 * pow(10.0, -8.0) * KhphosRBCvMGPHOS * pHConversionFactor) / (1.0 + hRBC * KhphosRBCvMGPHOS + KkphosRBCvMGPHOS * kRBC)

K3appRBCvBPGSP2 = 1.75857757502918 * K3RBCvBPGSP2 / (1.0 + 4.78630092322638 * pow(10.0, 28.0) / pow(10.0, 4.0 * phRBC))

KaappRBCvMGATP = CRBCvMGATP * KaRBCvMGATP * (hRBC * KhatpRBCvMGATP * KmghatpRBCvMGATP + KRBCvMGATP) / (1.0 + KkatpRBCvMGATP * kRBC + KhatpRBCvMGATP / (pow(10.0, phRBC) * pHConversionFactor))

K1appRBCvAK = K1RBCvAK * (1.0 + KkadpRBCvAK * kRBC + KhadpRBCvAK * pHConversionFactor / pow(10.0, phRBC))

HbpHRBC = (1.0 + 2.51188643150958 * pow(10.0, 14.0) * pow(KahbRBC, 2.0) / pow(pHConversionFactor, 2.0) + 3.16978638492223 * pow(10.0, 7.0) * KahbRBC / pHConversionFactor) / (1.0 + 2.0 * KahbRBC / hRBC + pow(KahbRBC, 2.0) / pow(hRBC, 2.0))

KaappRBCvMGB13PG = CRBCvMGB13PG * KaRBCvMGB13PG * (hRBC * KhbpgRBCvMGB13PG * KmghbpgRBCvMGB13PG + KRBCvMGB13PG) / (1.0 + hRBC * KhbpgRBCvMGB13PG + pow(hRBC, 2.0) * Kh2bpgRBCvMGB13PG * KhbpgRBCvMGB13PG + KkbpgRBCvMGB13PG * kRBC + hRBC * KhbpgRBCvMGB13PG * KkhbpgRBCvMGB13PG * kRBC)

Function definitions

Events

Constraints

Note that constraints are not enforced in simulations. It remains the responsibility of the user to verify that simulation results satisfy these constraints.

Snap to grid*

Show wireframe*

Show modifiers*

Show compartments*

Gravity*

Repulsion*

Pool threshold*

Species:

Reactions:

Middle-click: pin/unpin nodes
Shift-click: pool/unpool species
Right-click: context menu

Apply alternate model layout to overlapping elements in current model:

Model schema*

Start time*

End time*

log scales

y-axis min/max

x-axis min/max

Species

Rates

Assignment rules

Parameter*

Start*

End*

Steps*

Species

Rates

Assignment rules

Rate*

No manuscript information is available for this model.

No additional notes are available for this model.

JWS Online documentation

adpPF (adpPF)
adpRBCi (adpRBCi)
ampRBCi (ampRBCi)
atpPF (atpPF)
atpRBCi (atpRBCi)
b13pgPF (b13pgPF)
b13pgRBCi (b13pgRBCi)
b23pgRBCi (b23pgRBCi)
bpgspRBCi (bpgspRBCi)
bpgspb13pgRBCi (bpgspb13pgRBCi)
bpgspb23pgRBCi (bpgspb23pgRBCi)
bpgsppRBCi (bpgsppRBCi)
bpgsppp2gRBCi (bpgsppp2gRBCi)
bpgsppp3gRBCi (bpgsppp3gRBCi)
bpgsppphosRBCi (bpgsppphosRBCi)
dhapPF (dhapPF)
dhapRBCi (dhapRBCi)
ery4pRBCi (ery4pRBCi)
f16bpPF (f16bpPF)
f16p2RBCi (f16p2RBCi)
f6pPF (f6pPF)
f6pRBCi (f6pRBCi)
g16p2RBCi (g16p2RBCi)
g3pPF (g3pPF)
g6pPF (g6pPF)
g6pRBCi (g6pRBCi)
gapPF (gapPF)
gapRBCi (gapRBCi)
glcPF (glcPF)
glcRBCi (glcRBCi)
gshRBCi (gshRBCi)
gssgRBCi (gssgRBCi)
hbRBCi (hbRBCi)
hbadpRBCi (hbadpRBCi)
hbatpRBCi (hbatpRBCi)
hbb13pgRBCi (hbb13pgRBCi)
hbb23pgRBCi (hbb23pgRBCi)
hbmgatpRBCi (hbmgatpRBCi)
lacPF (lacPF)
lacRBCi (lacRBCi)
mgRBCi (mgRBCi)
mgadpRBCi (mgadpRBCi)
mgatpRBCi (mgatpRBCi)
mgb13pgRBCi (mgb13pgRBCi)
mgb23pgRBCi (mgb23pgRBCi)
mgf16p2RBCi (mgf16p2RBCi)
mgg16p2RBCi (mgg16p2RBCi)
mgphosRBCi (mgphosRBCi)
nadPF (nadPF)
nadRBCi (nadRBCi)
nadhPF (nadhPF)
nadhRBCi (nadhRBCi)
nadpRBCi (nadpRBCi)
nadphRBCi (nadphRBCi)
p2gPF (p2gPF)
p2gRBCi (p2gRBCi)
p3gPF (p3gPF)
p3gRBCi (p3gRBCi)
p6gRBCi (p6gRBCi)
p6glRBCi (p6glRBCi)
pepPF (pepPF)
pepRBCi (pepRBCi)
phosRBCi (phosRBCi)
pyrPF (pyrPF)
pyrRBCi (pyrRBCi)
rib5pRBCi (rib5pRBCi)
ru5pRBCi (ru5pRBCi)
sed7pRBCi (sed7pRBCi)
tkRBCi (tkRBCi)
tkgRBCi (tkgRBCi)
tkgery4pRBCi (tkgery4pRBCi)
tkgrib5pRBCi (tkgrib5pRBCi)
tkxu5pRBCi (tkxu5pRBCi)
xu5pRBCi (xu5pRBCi)

vPFvALD
vPFvATPASE
vPFvENO
vPFvG3PDH
vPFvGAPDH
vPFvGLCtr (vPFvGLCtr)
vPFvGLYtr (vPFvGLYtr)
vPFvHK
vPFvLACtr (vPFvLACtr)
vPFvLDH
vPFvPFK
vPFvPGI
vPFvPGK
vPFvPGM
vPFvPK
vPFvPYRtr (vPFvPYRtr)
vPFvTPI
vRBCivAK (vRBCivAK)
vRBCivALD (vRBCivALD)
vRBCivATPASE (vRBCivATPASE)
vRBCivBPGSP1 (vRBCivBPGSP1)
vRBCivBPGSP2 (vRBCivBPGSP2)
vRBCivBPGSP3 (vRBCivBPGSP3)
vRBCivBPGSP4 (vRBCivBPGSP4)
vRBCivBPGSP5 (vRBCivBPGSP5)
vRBCivBPGSP6 (vRBCivBPGSP6)
vRBCivBPGSP7 (vRBCivBPGSP7)
vRBCivBPGSP8 (vRBCivBPGSP8)
vRBCivBPGSP9 (vRBCivBPGSP9)
vRBCivENO (vRBCivENO)
vRBCivG6PDH (vRBCivG6PDH)
vRBCivGAPDH (vRBCivGAPDH)
vRBCivGLCTRANSPORT (vRBCivGLCTRANSPORT)
vRBCivGSSGR (vRBCivGSSGR)
vRBCivHBADP (vRBCivHBADP)
vRBCivHBATP (vRBCivHBATP)
vRBCivHBB13PG (vRBCivHBB13PG)
vRBCivHBB23PG (vRBCivHBB23PG)
vRBCivHBMGATP (vRBCivHBMGATP)
vRBCivHK (vRBCivHK)
vRBCivLACTRANSPORT (vRBCivLACTRANSPORT)
vRBCivLDH (vRBCivLDH)
vRBCivLDHP (vRBCivLDHP)
vRBCivMGADP (vRBCivMGADP)
vRBCivMGATP (vRBCivMGATP)
vRBCivMGB13PG (vRBCivMGB13PG)
vRBCivMGB23PG (vRBCivMGB23PG)
vRBCivMGF16P2 (vRBCivMGF16P2)
vRBCivMGG16P2 (vRBCivMGG16P2)
vRBCivMGPHOS (vRBCivMGPHOS)
vRBCivOX (vRBCivOX)
vRBCivOXNADH (vRBCivOXNADH)
vRBCivP6GDH (vRBCivP6GDH)
vRBCivPFK (vRBCivPFK)
vRBCivPGI (vRBCivPGI)
vRBCivPGK (vRBCivPGK)
vRBCivPGLHYDROLYSIS (vRBCivPGLHYDROLYSIS)
vRBCivPGM (vRBCivPGM)
vRBCivPHOSTRANSPORT (vRBCivPHOSTRANSPORT)
vRBCivPK (vRBCivPK)
vRBCivPYRTRANSPORT (vRBCivPYRTRANSPORT)
vRBCivR5PI (vRBCivR5PI)
vRBCivRu5PE (vRBCivRu5PE)
vRBCivTA (vRBCivTA)
vRBCivTIM (vRBCivTIM)
vRBCivTK1 (vRBCivTK1)
vRBCivTK2 (vRBCivTK2)
vRBCivTK3 (vRBCivTK3)
vRBCivTK4 (vRBCivTK4)
vRBCivTK5 (vRBCivTK5)
vRBCivTK6 (vRBCivTK6)

dutoit1

Reactions

vPFvALD

vPFvATPASE

vPFvENO

vPFvG3PDH

vPFvGAPDH

vPFvGLCtr

vPFvGLYtr

vPFvHK

vPFvLACtr

vPFvLDH

vPFvPFK

vPFvPGI

vPFvPGK

vPFvPGM

vPFvPK

vPFvPYRtr

vPFvTPI

vRBCivAK

vRBCivALD

vRBCivATPASE

vRBCivBPGSP1

vRBCivBPGSP2

vRBCivBPGSP3

vRBCivBPGSP4

vRBCivBPGSP5

vRBCivBPGSP6

vRBCivBPGSP7

vRBCivBPGSP8

vRBCivBPGSP9

vRBCivENO

vRBCivG6PDH

vRBCivGAPDH

vRBCivGLCTRANSPORT

vRBCivGSSGR

vRBCivHBADP

vRBCivHBATP

vRBCivHBB13PG

vRBCivHBB23PG

vRBCivHBMGATP

vRBCivHK

vRBCivLACTRANSPORT

vRBCivLDH

vRBCivLDHP

vRBCivMGADP

vRBCivMGATP

vRBCivMGB13PG

vRBCivMGB23PG

vRBCivMGF16P2

vRBCivMGG16P2

vRBCivMGPHOS

vRBCivOX

vRBCivOXNADH

vRBCivP6GDH

vRBCivPFK

vRBCivPGI

vRBCivPGK

vRBCivPGLHYDROLYSIS

vRBCivPGM

vRBCivPHOSTRANSPORT

vRBCivPK

vRBCivPYRTRANSPORT

vRBCivR5PI

vRBCivRu5PE

vRBCivTA

vRBCivTIM

vRBCivTK1

vRBCivTK2

vRBCivTK3

vRBCivTK4

vRBCivTK5

vRBCivTK6

Parameters

Fixed species

Initial values

Functions and Rules

Assignment rules

Function definitions

Events