chance2
The SBML for this model was obtained from the BioModels database (BioModels ID: BIOMD0000000282) Biomodels notes: Reproduction of figure 3 of the original publication. The simulations were performed using SBML ODEsolver with varying initial concentrations of the substrate, hydrogen peroxide, x. The time courses are slightly different from the published ones, which most likely is due to the completely different integrators used. JWS Online curation: This model was curated by reproducing the figures as described in the BioModels Notes. No additional changes were made.
None
None
None
None
None
None
Unit definitions have no effect on the numerical analysis of the model. It remains the responsibility of the modeler to ensure the internal numerical consistency of the model. If units are provided, however, the consistency of the model units will be checked.
| Name | Definition | |
|---|---|---|
| — | 1e-06 mole | |
| — | 1000000.0 mole^(-1.0) litre second^(-1.0) | |
| — | 0.1 second^(-1.0) |
| Id | Name | Spatial dimensions | Size | |
|---|---|---|---|---|
| cell | cell | 3.0 | 1.0 |
| Id | Name | Initial quantity | Compartment | Fixed | |
|---|---|---|---|---|---|
| a | donor AH2 | 0.0 | cell (cell) | ✔ | |
| e | enzyme E (catalase) | 1.36 | cell (cell) | ✘ | |
| p | enzyme-substrate complex ES (catalase - hydrogen peroxide) | 0.0 | cell (cell) | ✘ | |
| p1 | product 1 | 0.0 | cell (cell) | ✘ | |
| p2 | product 2 | 0.0 | cell (cell) | ✘ | |
| x | substrate S (hydrogen peroxide) | 2.0 | cell (cell) | ✘ |
Initial assignments are expressions that are evaluated at time=0. It is not recommended to create initial assignments for all model entities. Restrict the use of initial assignments to cases where a value is expressed in terms of values or sizes of other model entities. Note that it is not permitted to have both an initial assignment and an assignment rule for a single model entity.
| Definition |
|---|
| Id | Name | Objective coefficient | Reaction Equation and Kinetic Law | Flux bounds | |
|---|---|---|---|---|---|
| r1 | r1 | e + x = p cell * (k1 * e * x - k2 * p) | |||
| r2 | r2 | p + x > e + p1 cell * k4_prime * p * x | |||
| r3 | r3 | p + a > e + p2 cell * k4 * p * a |
| Id | Value | |
|---|---|---|
| k1 | 11.0 | |
| k2 | 0.0 | |
| k4 | 0.72 | |
| k4_prime | 16.6 |
| Id | Value | Reaction |
|---|
| Definition |
|---|
| Definition |
|---|
| Definition |
|---|
| Definition |
|---|
| Trigger | Assignments |
|---|